Influenza-induced rhabdomyolysis

Martin Runnstrom, Alex M. Ebied, Adonice Paul Khoury, Raju Reddy

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Rhabdomyolysis is characterised by muscle breakdown with release of damaging proteins that can have devastating consequences. Acute influenza infection is being increasingly recognised as an underlying aetiology. We report an unusual case of severe rhabdomyolysis with acute renal failure due to influenza A infection that improved with high-dose oseltamivir and intravenous fluids. In our case, we also noticed a temporal relation between fever spikes and subsequent increase in serum creatine kinase. The precise mechanism between the rise in temperature and creatine kinase is unclear but it could be due to direct viral invasion of myocytes or due to release of new viral progeny following replication in the myocyte.

Original languageEnglish (US)
Article numbere226610
JournalBMJ Case Reports
Volume11
Issue number1
DOIs
StatePublished - Dec 1 2018
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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