Infant vision and retinal function in studies of dietary long-chain polyunsaturated fatty acids: Methods, results, and implications

    Research output: Contribution to journalArticle

    105 Scopus citations

    Abstract

    Animal and human studies have documented several effects of different dietary and tissue concentrations of long-chain polyunsaturated fatty acids (LCPUFAs) on retinal function and vision. The enhanced Visual development associated with increased intakes of LCPUFAs, particularly docosahexaenoic acid (DHA), provides the strongest evidence for the importance of these fatty acids in infant nutrition. The 2 primary visual measures used to assess the efficacy of infant formula LCPUFA supplementation are the electroretinogram and visual acuity. This review briefly describes the methodology, neural basis, and interpretation of these measures, as well as other measures of visual development that may be used to extend the functional evaluation of infants fed formulas with different fatty acid compositions.

    Original languageEnglish (US)
    Pages (from-to)256S-267S
    JournalAmerican Journal of Clinical Nutrition
    Volume71
    Issue number1 SUPPL.
    DOIs
    StatePublished - Jan 2000

    Keywords

    • Docosahexaenoic acid
    • Electroretinogram
    • Infant nutrition
    • Long-chain polyunsaturated fatty acids
    • Retina
    • Visual acuity
    • Visual development
    • n-3 fatty acids

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • Nutrition and Dietetics

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