Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder

D. C. Dawson, Q. Al-Awqati

Research output: Contribution to journalArticle

5 Scopus citations


When active Na+ transport across the toad urinary bladder was abolished by ouabain, a 'reversed' short circuit current could be induced by an Na+ concentration gradient. This reversed current was increased by vasopressin and inhibited by amiloride and appears to represent net Na+ movement 'backwards' through epithelial cells which normally participate in active Na+ transport across the bladder.

Original languageEnglish (US)
Pages (from-to)413-417
Number of pages5
JournalBBA - Biomembranes
Issue number2
StatePublished - Apr 4 1978


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Cell Biology

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