Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder

D. C. Dawson; Q. Al-Awqati

doi:10.1016/0005-2736(78)90343-7

Induction of reverse flow of Na⁺ through the active transport pathway in toad urinary bladder

D. C. Dawson, Q. Al-Awqati

Physiology & Pharmacology

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

When active Na⁺ transport across the toad urinary bladder was abolished by ouabain, a 'reversed' short circuit current could be induced by an Na⁺ concentration gradient. This reversed current was increased by vasopressin and inhibited by amiloride and appears to represent net Na⁺ movement 'backwards' through epithelial cells which normally participate in active Na⁺ transport across the bladder.

Original language	English (US)
Pages (from-to)	413-417
Number of pages	5
Journal	BBA - Biomembranes
Volume	508
Issue number	2
DOIs	https://doi.org/10.1016/0005-2736(78)90343-7
State	Published - Apr 4 1978

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ASJC Scopus subject areas

Biophysics
Biochemistry
Cell Biology

Cite this

Dawson, D. C., & Al-Awqati, Q. (1978). Induction of reverse flow of Na⁺ through the active transport pathway in toad urinary bladder. BBA - Biomembranes, 508(2), 413-417. https://doi.org/10.1016/0005-2736(78)90343-7

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Access to Document

10.1016/0005-2736(78)90343-7