Increased cytosolic free sodium in platelets from patients with early-stage chronic renal failure

E. A. Burdmann, T. F. Andoh, J. Lindsley, Donald Houghton, W. M. Bennett

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Cytosolic free sodium concentration ([Na+]t) and sodium transport systems were measured in intact platelets from 19 patients with early-stage chronic renal failure and 33 healthy control subjects using the novel fluorescent dye sodium-bindingbenzofuran- isophthalate. Resting [Na+] was significantly greater in patients with chronic renal failure compared to control subjects (40.8 ±3.1 mmol/1 versus 32.2 ± 2.0 mmol/1, mean±SEM, P

Original languageEnglish (US)
Pages (from-to)27-34
Number of pages8
JournalNephrology Dialysis Transplantation
Volume9
Issue number1
DOIs
StatePublished - 1994

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Chronic Kidney Failure
Blood Platelets
Sodium
Fluorescent Dyes
Healthy Volunteers
isophthalate

Keywords

  • Chronic renal failure
  • Fluorescent dye
  • Platelets
  • Sodium

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

Cite this

Increased cytosolic free sodium in platelets from patients with early-stage chronic renal failure. / Burdmann, E. A.; Andoh, T. F.; Lindsley, J.; Houghton, Donald; Bennett, W. M.

In: Nephrology Dialysis Transplantation, Vol. 9, No. 1, 1994, p. 27-34.

Research output: Contribution to journalArticle

Burdmann, E. A. ; Andoh, T. F. ; Lindsley, J. ; Houghton, Donald ; Bennett, W. M. / Increased cytosolic free sodium in platelets from patients with early-stage chronic renal failure. In: Nephrology Dialysis Transplantation. 1994 ; Vol. 9, No. 1. pp. 27-34.
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