Abstract
Cardiac rhabdomyoma, a rare benign tumor often detected in infancy, is frequently associated with tuberous sclerosis. This association is commonly stated to occur in 50% of all cases of cardiac rhabdomyoma. Recently at our institution, the prenatal detection of a cardiac rhabdomyoma in a fetus at no known risk for tuberous sclerosis emphasized the need to determine the frequency of association in order to provide accurate diagnosis and counseling in such situations. After a review of reported cases and review of patients from our institution diagnosed to have cardiac rhabdomyoma, we estimate that 51-86% of cardiac rhabdomyomas are associated with tuberous sclerosis. We present the results of our literature and case review.
Original language | English (US) |
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Pages (from-to) | 443-446 |
Number of pages | 4 |
Journal | American Journal of Medical Genetics |
Volume | 37 |
Issue number | 4 |
DOIs | |
State | Published - 1990 |
Externally published | Yes |
Keywords
- infancy
- prenatal diagnosis
- rare benign tumor
ASJC Scopus subject areas
- Genetics(clinical)