In vitro validation of tissue doppler left ventricular regional wall velocities by using a novel balloon phantom

Ying Wu, Timothy Irvine, Yoshiki Mori, Xiaokui Li, David Sahn

Research output: Contribution to journalArticle

Abstract

To investigate the validity and accuracy of tissue Doppler imaging (TDI) using a novel balloon phantom, validation of TDI myocardial velocity measurements has been carried out indirectly from conventional M-mode images. However it is not a true and independent gold standard. We described a new TDI validation method by using a specially developed left ventricular balloon model mounted in a water bath and constructed using two pear-shaped balloons. It was connected to a pulsatile flow pump at 8 stroke volumes (50-85 ml/beat). The displacement and velocity of the balloon walls were recorded simultaneously by video imaging and TDI on a GE-Vingmed System Five with a 5 MHz phased array probe at the highest frame rates available. Conventional M-mode and 2-D imaging verified that our balloon model mimicked the shape and wall motion of left ventricle. There was a good correlation and agreement between the maximum video excursion of the anterior and posterior walls of the phantom and the results of the temporal integration of digital distance data by TDI (Anterior wall: r = 0. 97, SEE = 0. 24 mm, x̄±s = 0. 04 ± 0. 24 mm: Posterior wall: r = 0. 95, SEE = 0. 22 mm, x̄±s = 0. 03 ± 0. 24 mm). Analysis of the velocity profile by the TDI method showed that the velocity at each measured point was correlated well with the velocity obtained from the video images (Anterior wall: r = 0. 97, SEE = 0. 30 mm, x̄±s = - 0. 04 ± 0. 28 mm: Posterior wall: r = 0. 97, SEE = 0. 30 mm, x̄±s = 0. 04 ± 0. 28 mm). Our balloon model provided a new independent method for the validation of TDI data. This study demonstrated that the present TDI system is reliable for measuring wall motion distance and velocity.

Original languageEnglish (US)
Pages (from-to)337-340
Number of pages4
JournalJournal of Huazhong University of Science and Technology - Medical Science
Volume21
Issue number4
StatePublished - 2001

Fingerprint

Balloons
Tissue
Imaging techniques
Pulsatile Flow
Pyrus
In Vitro Techniques
Imaging
Pulsatile flow
Baths
Stroke Volume
Heart Ventricles
Imaging systems
Velocity measurement
Pumps
Water

Keywords

  • In vitro
  • Left ventricular regional velocity
  • Tissue Doppler imaging

ASJC Scopus subject areas

  • Management of Technology and Innovation

Cite this

In vitro validation of tissue doppler left ventricular regional wall velocities by using a novel balloon phantom. / Wu, Ying; Irvine, Timothy; Mori, Yoshiki; Li, Xiaokui; Sahn, David.

In: Journal of Huazhong University of Science and Technology - Medical Science, Vol. 21, No. 4, 2001, p. 337-340.

Research output: Contribution to journalArticle

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