Improvement in corneal scarring following bacterial keratitis

Scott McClintic, M. Srinivasan, J. Mascarenhas, D. A. Greninger, N. R. Acharya, T. M. Lietman, J. D. Keenan

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

AimBacterial keratitis results in corneal scarring and subsequent visual impairment. The long-term evolution of corneal scars has not been well described. In this case series, we identified patients who had improvement in corneal scarring and visual acuity from a clinical trial for bacterial keratitis.MethodsWe searched the records of the Steroids for Corneal Ulcers Trial (SCUT) for patients who had improvement in vision between the 3-month and 12-month visits and reviewed their clinical photographs.ResultsOf the 500 patients enrolled in SCUT, five patients with large central corneal scars due to bacterial keratitis are presented. All experienced improvement in rigid contact lens-corrected visual acuity from months 3 to 12. All patients also had marked improvement in corneal opacity during the same time period. None of the patients opted to have penetrating keratoplasty.ConclusionsCorneal scars may continue to improve even many months after a bacterial corneal ulcer has healed. The corneal remodeling can be accompanied by considerable improvement in visual acuity, such that corneal transplantation may not be necessary.

Original languageEnglish (US)
Pages (from-to)443-446
Number of pages4
JournalEye (Basingstoke)
Volume27
Issue number3
DOIs
StatePublished - Mar 2013
Externally publishedYes

Fingerprint

Keratitis
Cicatrix
Corneal Ulcer
Visual Acuity
Steroids
Corneal Opacity
Penetrating Keratoplasty
Corneal Transplantation
Vision Disorders
Contact Lenses
Clinical Trials

Keywords

  • corneal scar
  • corneal ulcer
  • SCUT

ASJC Scopus subject areas

  • Ophthalmology

Cite this

McClintic, S., Srinivasan, M., Mascarenhas, J., Greninger, D. A., Acharya, N. R., Lietman, T. M., & Keenan, J. D. (2013). Improvement in corneal scarring following bacterial keratitis. Eye (Basingstoke), 27(3), 443-446. https://doi.org/10.1038/eye.2012.270

Improvement in corneal scarring following bacterial keratitis. / McClintic, Scott; Srinivasan, M.; Mascarenhas, J.; Greninger, D. A.; Acharya, N. R.; Lietman, T. M.; Keenan, J. D.

In: Eye (Basingstoke), Vol. 27, No. 3, 03.2013, p. 443-446.

Research output: Contribution to journalArticle

McClintic, S, Srinivasan, M, Mascarenhas, J, Greninger, DA, Acharya, NR, Lietman, TM & Keenan, JD 2013, 'Improvement in corneal scarring following bacterial keratitis', Eye (Basingstoke), vol. 27, no. 3, pp. 443-446. https://doi.org/10.1038/eye.2012.270
McClintic S, Srinivasan M, Mascarenhas J, Greninger DA, Acharya NR, Lietman TM et al. Improvement in corneal scarring following bacterial keratitis. Eye (Basingstoke). 2013 Mar;27(3):443-446. https://doi.org/10.1038/eye.2012.270
McClintic, Scott ; Srinivasan, M. ; Mascarenhas, J. ; Greninger, D. A. ; Acharya, N. R. ; Lietman, T. M. ; Keenan, J. D. / Improvement in corneal scarring following bacterial keratitis. In: Eye (Basingstoke). 2013 ; Vol. 27, No. 3. pp. 443-446.
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