Immune cells and inflammatory mediators as regulators of tumor angiogenesis

Michele De Palma, Lisa M. Coussens

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Scopus citations

Abstract

Tumors conscript immune cells to support neoplastic progression. One important mechanism by which immune cells contribute to tumor growth is the promotion of angiogenesis. In this chapter, we discuss the role of immune cells and inflammatory mediators in this process. Targeting immune cells and their proangiogenic programs in tumors may represent a new frontier of antiangiogenic therapy.

Original languageEnglish (US)
Title of host publicationAngiogenesis
Subtitle of host publicationAn Integrative Approach From Science to Medicine
PublisherSpringer US
Pages225-237
Number of pages13
ISBN (Print)9780387715179
DOIs
StatePublished - Dec 1 2008

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Keywords

  • angiogenesis
  • cancer
  • immune cells
  • inflammation
  • leukocytes
  • monocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

De Palma, M., & Coussens, L. M. (2008). Immune cells and inflammatory mediators as regulators of tumor angiogenesis. In Angiogenesis: An Integrative Approach From Science to Medicine (pp. 225-237). Springer US. https://doi.org/10.1007/978-0-387-71518-6_20