TY - JOUR
T1 - Imaging hypoxia and angiogenesis in tumors
AU - Rajendran, Joseph G.
AU - Krohn, Kenneth A.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2005/1
Y1 - 2005/1
N2 - There is a clear need in cancer treatment for a noninvasive imaging assay that evaluates the oxygenation status and heterogeneity of hypoxia and angiogenesis in individual patients. Such an assay could be used to select alternative treatments and to monitor the effects of treatment. Of the several methods available, each imaging procedure has at least one disadvantage. Rather than develop new and improved hypoxia agents, or even quibbling about the pros and cons of alternative agents, the nuclear medicine community needs to convince the oncology community that imaging hypoxia is an important procedure that can lead to improved treatment outcome.
AB - There is a clear need in cancer treatment for a noninvasive imaging assay that evaluates the oxygenation status and heterogeneity of hypoxia and angiogenesis in individual patients. Such an assay could be used to select alternative treatments and to monitor the effects of treatment. Of the several methods available, each imaging procedure has at least one disadvantage. Rather than develop new and improved hypoxia agents, or even quibbling about the pros and cons of alternative agents, the nuclear medicine community needs to convince the oncology community that imaging hypoxia is an important procedure that can lead to improved treatment outcome.
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U2 - 10.1016/j.rcl.2004.08.004
DO - 10.1016/j.rcl.2004.08.004
M3 - Review article
C2 - 15693655
AN - SCOPUS:13944273440
VL - 43
SP - 169
EP - 187
JO - Radiologic Clinics of North America
JF - Radiologic Clinics of North America
SN - 0033-8389
IS - 1
ER -