Imaging hypoxia and angiogenesis in tumors

Joseph G. Rajendran; Kenneth A. Krohn

doi:10.1016/j.rcl.2004.08.004

Imaging hypoxia and angiogenesis in tumors

Joseph G. Rajendran, Kenneth A. Krohn

Research output: Contribution to journal › Review article › peer-review

142 Scopus citations

Abstract

There is a clear need in cancer treatment for a noninvasive imaging assay that evaluates the oxygenation status and heterogeneity of hypoxia and angiogenesis in individual patients. Such an assay could be used to select alternative treatments and to monitor the effects of treatment. Of the several methods available, each imaging procedure has at least one disadvantage. Rather than develop new and improved hypoxia agents, or even quibbling about the pros and cons of alternative agents, the nuclear medicine community needs to convince the oncology community that imaging hypoxia is an important procedure that can lead to improved treatment outcome.

Original language	English (US)
Pages (from-to)	169-187
Number of pages	19
Journal	Radiologic Clinics of North America
Volume	43
Issue number	1
DOIs	https://doi.org/10.1016/j.rcl.2004.08.004
State	Published - Jan 2005
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.rcl.2004.08.004

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AB - There is a clear need in cancer treatment for a noninvasive imaging assay that evaluates the oxygenation status and heterogeneity of hypoxia and angiogenesis in individual patients. Such an assay could be used to select alternative treatments and to monitor the effects of treatment. Of the several methods available, each imaging procedure has at least one disadvantage. Rather than develop new and improved hypoxia agents, or even quibbling about the pros and cons of alternative agents, the nuclear medicine community needs to convince the oncology community that imaging hypoxia is an important procedure that can lead to improved treatment outcome.

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Imaging hypoxia and angiogenesis in tumors

Abstract

ASJC Scopus subject areas

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