TY - JOUR
T1 - Idiopathic myelofibrosis
T2 - dental treatment considerations
AU - Steelman, Robert
AU - Holmes, Douglas
AU - Cranston, Roberta
AU - Cupp, Dolly
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1991/3
Y1 - 1991/3
N2 - Idiopathic myelofibrosis is a myeloproliferative disorder of unknown origin. The bone marrow becomes fibrotic with an associated decrease in hematopoiesis resulting in anemia, bleeding problems, splenomegaly, and other secondary abnormalities. Although idiopathic myelofibrosis is usually diagnosed in middle age, there have been a few reports of the disorder in the pediatric population. This case report documents dental treatment considerations in a 6‐year‐old female with idiopathic myelofibrosis, severe anemia, and abnormal blood coagulation studies. The patient was successfully treated in a hospital after medical consultation, transfusion of packed red blood cells, and administration of prophylactic antibiotics. Local hemostatic measures following multiple extractions of carious teeth controlled bleeding. No postoperative sequelae occurred.
AB - Idiopathic myelofibrosis is a myeloproliferative disorder of unknown origin. The bone marrow becomes fibrotic with an associated decrease in hematopoiesis resulting in anemia, bleeding problems, splenomegaly, and other secondary abnormalities. Although idiopathic myelofibrosis is usually diagnosed in middle age, there have been a few reports of the disorder in the pediatric population. This case report documents dental treatment considerations in a 6‐year‐old female with idiopathic myelofibrosis, severe anemia, and abnormal blood coagulation studies. The patient was successfully treated in a hospital after medical consultation, transfusion of packed red blood cells, and administration of prophylactic antibiotics. Local hemostatic measures following multiple extractions of carious teeth controlled bleeding. No postoperative sequelae occurred.
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U2 - 10.1111/j.1754-4505.1991.tb00818.x
DO - 10.1111/j.1754-4505.1991.tb00818.x
M3 - Article
C2 - 1831296
AN - SCOPUS:0026130191
SN - 0275-1879
VL - 11
SP - 68
EP - 70
JO - Special Care in Dentistry
JF - Special Care in Dentistry
IS - 2
ER -