Identification of fibrin/fibrinogen in glaucoma filtration surgery wounds.

H. D. Jampel, John Morrison, M. Vocci, H. Quigley

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We have localized fibrin/fibrinogen in experimental glaucoma filtration surgery wounds in non-human primates by light and transmission electron microscopy. Fibrin/fibrinogen was abundant two days after surgery, but was virtually undetectable by seven days postoperatively. We have confirmed the identity of fibrin/fibrinogen on the ultrastructural level by immunoelectron microscopy employing antibodies directed against fibrinogen. Fibrin clot formation may play an important role in the wound healing response that causes glaucoma filtration surgery to fail.

Original languageEnglish (US)
Pages (from-to)576-579
Number of pages4
JournalOphthalmic Surgery
Volume19
Issue number8
StatePublished - Aug 1988
Externally publishedYes

Fingerprint

Filtering Surgery
Fibrin
Glaucoma
Fibrinogen
Wounds and Injuries
Immunoelectron Microscopy
Transmission Electron Microscopy
Ambulatory Surgical Procedures
Wound Healing
Primates
Light
Antibodies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Identification of fibrin/fibrinogen in glaucoma filtration surgery wounds. / Jampel, H. D.; Morrison, John; Vocci, M.; Quigley, H.

In: Ophthalmic Surgery, Vol. 19, No. 8, 08.1988, p. 576-579.

Research output: Contribution to journalArticle

Jampel, HD, Morrison, J, Vocci, M & Quigley, H 1988, 'Identification of fibrin/fibrinogen in glaucoma filtration surgery wounds.', Ophthalmic Surgery, vol. 19, no. 8, pp. 576-579.
Jampel, H. D. ; Morrison, John ; Vocci, M. ; Quigley, H. / Identification of fibrin/fibrinogen in glaucoma filtration surgery wounds. In: Ophthalmic Surgery. 1988 ; Vol. 19, No. 8. pp. 576-579.
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