Identification of fibrin/fibrinogen in glaucoma filtration surgery wounds.

H. D. Jampel, J. Morrison, M. Vocci, H. Quigley

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

We have localized fibrin/fibrinogen in experimental glaucoma filtration surgery wounds in non-human primates by light and transmission electron microscopy. Fibrin/fibrinogen was abundant two days after surgery, but was virtually undetectable by seven days postoperatively. We have confirmed the identity of fibrin/fibrinogen on the ultrastructural level by immunoelectron microscopy employing antibodies directed against fibrinogen. Fibrin clot formation may play an important role in the wound healing response that causes glaucoma filtration surgery to fail.

Original languageEnglish (US)
Pages (from-to)576-579
Number of pages4
JournalOphthalmic surgery
Volume19
Issue number8
StatePublished - Aug 1988

ASJC Scopus subject areas

  • Ophthalmology

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