Abstract
Density gradient ultracentrifugation and high resolution polyacrylamide gel electrophoresis (Lipoprint LDL-system) were used to examine the discrete LDL subfraction patterns in normal and hyperlipidemic patients. Two new programs for LDL and VLDL subfractions were elaborated and a new method of evaluation for cholesterol content in LDL-subfractions, based on area distribution ratio of densitograms without density gradient ultracentrifugation, was created. The predominance of cholesterol and triglycerides in dense LDL3-subclass (d-1,048-1,063 g/ml) under hypercholesterolemia and hypertriglyceridemia was found. Lipoprint LDL-electrophoresis method was developed for the characteristic of lipemic state of organism and detection and quantitation of plasma LDL subfractions.
Original language | English (US) |
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Pages (from-to) | 60-65 |
Number of pages | 6 |
Journal | Ukrainskii biokhimicheskii zhurnal |
Volume | 67 |
Issue number | 6 |
State | Published - 1995 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry