Hypotony Maculopathy: Clinical Presentation and Therapeutic Methods

Merina Thomas, Thasarat S. Vajaranant, Ahmad A. Aref

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


Introduction: Hypotony maculopathy is ocular hypotony complicated by papilledema and/or folding of the retina and choroid in the posterior pole. Our objective was to examine the current literature regarding hypotony maculopathy and treatment methods. Methods: A systematic review of the English-language literature was conducted by performing a broad search of PubMed from 1972 through 2015 using the keywords hypotony maculopathy and hypotony. Additional articles were identified from bibliographies of relevant articles. Results: Hypotony maculopathy was infrequent before the introduction of antimetabolite agents in glaucoma-filtering surgery, and the incidence of this entity is now up to 20%. Risk factors for developing hypotony maculopathy include male gender, young age, myopia, and primary filtering surgery. Correctly identifying the etiology of hypotony is essential for successful treatment. Treatment of hypotony maculopathy includes procedures to elevate the intraocular pressure, thus reversing the collapse of the scleral wall and chorioretinal wrinkling. Conclusion: This review discusses the definition, clinical presentation, pathophysiology, incidence and risk factors, prevention and treatment of hypotony maculopathy.

Original languageEnglish (US)
Pages (from-to)79-88
Number of pages10
JournalOphthalmology and Therapy
Issue number2
StatePublished - Dec 1 2015
Externally publishedYes


  • Glaucoma filtration surgery
  • Hypotony
  • Hypotony maculopathy
  • Retina

ASJC Scopus subject areas

  • Ophthalmology


Dive into the research topics of 'Hypotony Maculopathy: Clinical Presentation and Therapeutic Methods'. Together they form a unique fingerprint.

Cite this