Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology

Elizabeth M C Fisher, Tiina Alitalo, Shiuh-Wen Luoh, Albert de la Chapelle, David C. Page

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Several categories of human X-Y homologous DNA sequences have been recognized. We report that a locus (DXYS77) approximately 14 kb distal to the pseudoautosomal boundary (PAB) is 93% identical in nucleotide sequence to a locus (DYS148) on the long arm of the Y chromosome (Yq). Within this segment of pseudoautosomal/Yq homology we identified a member of a family of repeats that are concentrated in Xp22.3 and in the euchromatic portion of the Y chromosome. The repeat sequence structure-a dimer bounded by short terminal repeats-is reminiscent of retroposons derived from RNA polymerase III transcripts.

Original languageEnglish (US)
Pages (from-to)625-628
Number of pages4
JournalGenomics
Volume7
Issue number4
DOIs
StatePublished - 1990
Externally publishedYes

Fingerprint

Sex Chromosomes
Y Chromosome
Human Chromosomes
RNA Polymerase III
Retroelements
Terminal Repeat Sequences
Sequence Homology
Pseudoautosomal Regions

ASJC Scopus subject areas

  • Genetics

Cite this

Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology. / Fisher, Elizabeth M C; Alitalo, Tiina; Luoh, Shiuh-Wen; de la Chapelle, Albert; Page, David C.

In: Genomics, Vol. 7, No. 4, 1990, p. 625-628.

Research output: Contribution to journalArticle

Fisher, Elizabeth M C ; Alitalo, Tiina ; Luoh, Shiuh-Wen ; de la Chapelle, Albert ; Page, David C. / Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology. In: Genomics. 1990 ; Vol. 7, No. 4. pp. 625-628.
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