Human embryonic stem cell derivation and nuclear transfer: Impact on regenerative therapeutics and drug discovery

R. P. Cervera, M. Stojkovic

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

This review aims to introduce current and future uses of human embryonic stem cells derived from in vitro-fertilized embryos. These and stem cells derived from parthenogenetic and nuclear transfer embryos could be used for cell therapy, as in vitro cell models for drug discovery/screening, and for studying early human development and pathogenesis of human diseases. However, development of therapeutic and screening applications and products from embryonic stem cells is hampered by several barriers. Therefore, gaps in our current understanding of the basic science of stem cells need to be filled before either application can move forward with confidence.

Original languageEnglish (US)
Pages (from-to)310-315
Number of pages6
JournalClinical pharmacology and therapeutics
Volume82
Issue number3
DOIs
StatePublished - Sep 2007
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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