The authors report a case of post-LASIK interface fluid syndrome that led to epithelial ingrowth, a sequelae that had not been reported to date. The interface fluid was caused by steroid-induced ocular hypertension. On post-LASIK day 49, the interface fluid, epithelial ingrowth, and noncellular reflective deposits were visualized by confocal microscopy and high-resolution Fourier-domain optical coherence tomography. No inflammatory cells or infectious organisms were seen. These high-resolution imaging technologies were useful in the noninvasive evaluation of the location and nature of flap interface pathologies at the microstructural level.
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