High-frequency dynamics of regularly discharging canal afferents provide a linear signal for angular vestibuloocular reflexes

Timothy Hullar, Lloyd B. Minor

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Regularly discharging vestibular-nerve afferents innervating the semicircular canals were recorded extracellularly in anesthetized chinchillas undergoing high-frequency, high-velocity sinusoidal rotations. In the range from 2 to 20 Hz, with peak velocities of 151°/s at 6 Hz and 52°/s at 20 Hz, 67/70 (96%) maintained modulated discharge throughout the sinusoidal stimulus cycle without inhibitory cutoff or excitatory saturation. These afferents showed little harmonic distortion, no dependence of sensitivity on peak amplitude of stimulation, and no measurable half-cycle asymmetry. A transfer function fitting the data predicts no change in sensitivity (gain) of regularly discharging afferents over the frequencies tested but shows a phase lead with regard to head velocity increasing from 0°at 2 Hz to 30°at 20 Hz. These results indicate that regularly discharging afferents provide a plausible signal to drive the angular vestibuloocular reflex (VOR) even during high-frequency head motion but are not a likely source for nonlinearities present in the VOR.

Original languageEnglish (US)
Pages (from-to)2000-2005
Number of pages6
JournalJournal of Neurophysiology
Volume82
Issue number4
StatePublished - 1999
Externally publishedYes

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Vestibulo-Ocular Reflex
Head
Chinchilla
Vestibular Nerve
Semicircular Canals

ASJC Scopus subject areas

  • Physiology
  • Neuroscience(all)

Cite this

High-frequency dynamics of regularly discharging canal afferents provide a linear signal for angular vestibuloocular reflexes. / Hullar, Timothy; Minor, Lloyd B.

In: Journal of Neurophysiology, Vol. 82, No. 4, 1999, p. 2000-2005.

Research output: Contribution to journalArticle

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