Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis

the HRC neurodevelopmental follow-up investigators

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We questioned whether a heart rate characteristics (HRC) sepsis risk score displayed to clinicians would modify 18–22 month neurodevelopmental outcomes for extremely low birthweight infants who develop sepsis. Infants allocated to HRC display with sepsis had a 12% absolute reduction in the composite outcome of death or neurodevelopmental impairment. Trial registration: NCT00307333

Original languageEnglish (US)
Article number105419
JournalEarly Human Development
Volume159
DOIs
StatePublished - Aug 2021

Keywords

  • Extremely low birth weight, ELBW
  • Heart rate characteristics, HRC
  • Heart rate variability, HRV
  • Infant
  • Infant health
  • Infant, extremely low birth weight
  • Infant, extremely premature
  • Late onset sepsis, LOS
  • NICU
  • Neurodevelopmental impairment, NDI
  • Newborn infant
  • Randomized controlled trial, RCT

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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