Glycolide copolymer staple-line reinforcement reduces staple site bleeding during laparoscopic gastric bypass

A prospective randomized trial

Ninh T. Nguyen, Mario Longoria, Susan Welbourne, Allen Sabio, Samuel E. Wilson, James E. Goodnight, Lawrence A. Danto, Myriam Curet, Donald McConnell

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Hypothesis: The use of staple-line reinforcement sleeves during laparoscopic gastric bypass reduces staple-line bleeding, which may translate into a reduction in the rate of gastrointestinal hemorrhage. Design: Prospective randomized trial. Setting: University hospital. Patients and Interventions: Thirty-four patients undergoing laparoscopic gastric bypass were randomly assigned to receive either no reinforcement (control group, n=17) or reinforcement of the staple line with glycolic copolymer sleeves (treatment group, n=17). Main Outcome Measures: Demographic data, the number of stapler loads used, the number of staple-line bleeding sites, the amount of blood loss, the length of time required to obtain hemostasis of the staple lines, operative time, intraoperative and postoperative complications, and serial hemoglobin levels. Results: The mean number of stapler loads used was similar between groups. The mean number of staple-line bleeding sites was significantly fewer in the treatment group for division of gastric tissue (0.4 vs 2.5 bleeding sites), jejunal tissue (0.1 vs 0.6 bleeding site), and mesenteric tissue (0 vs 0.8 bleeding site). The mean blood loss was lower in the treatment group (84 vs 129 mL). Staple misfire occurred in 1 (0.7%) of 143 stapler loads used in the treatment group compared with 0 (0%) of 138 stapler loads used in the control group. The time to obtain stapleline hemostasis was shorter in the treatment group (1.2 vs 10.1 minutes). The total operative time was similar between groups. There was no mortality or postoperative leaks. One patient in the control group had postoperative gastrointestinal hemorrhage requiring blood transfusion and reoperation. There was no significant difference in the mean hemoglobin level between groups on the first postoperative day. Conclusions: The use of glycolide copolymer stapleline reinforcement sleeves in patients undergoing laparoscopic gastric bypass is safe and significantly reduces staple-line bleeding sites and may reduce the incidence of gastrointestinal hemorrhage.

Original languageEnglish (US)
Pages (from-to)773-778
Number of pages6
JournalArchives of Surgery
Volume140
Issue number8
DOIs
StatePublished - Aug 2005
Externally publishedYes

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Gastric Bypass
Hemorrhage
Gastrointestinal Hemorrhage
Operative Time
Hemostasis
Control Groups
Hemoglobins
Therapeutics
Postoperative Hemorrhage
Intraoperative Complications
Reoperation
Blood Transfusion
Stomach
Demography
Outcome Assessment (Health Care)
Mortality
Incidence

ASJC Scopus subject areas

  • Surgery

Cite this

Nguyen, N. T., Longoria, M., Welbourne, S., Sabio, A., Wilson, S. E., Goodnight, J. E., ... McConnell, D. (2005). Glycolide copolymer staple-line reinforcement reduces staple site bleeding during laparoscopic gastric bypass: A prospective randomized trial. Archives of Surgery, 140(8), 773-778. https://doi.org/10.1001/archsurg.140.8.773

Glycolide copolymer staple-line reinforcement reduces staple site bleeding during laparoscopic gastric bypass : A prospective randomized trial. / Nguyen, Ninh T.; Longoria, Mario; Welbourne, Susan; Sabio, Allen; Wilson, Samuel E.; Goodnight, James E.; Danto, Lawrence A.; Curet, Myriam; McConnell, Donald.

In: Archives of Surgery, Vol. 140, No. 8, 08.2005, p. 773-778.

Research output: Contribution to journalArticle

Nguyen, NT, Longoria, M, Welbourne, S, Sabio, A, Wilson, SE, Goodnight, JE, Danto, LA, Curet, M & McConnell, D 2005, 'Glycolide copolymer staple-line reinforcement reduces staple site bleeding during laparoscopic gastric bypass: A prospective randomized trial', Archives of Surgery, vol. 140, no. 8, pp. 773-778. https://doi.org/10.1001/archsurg.140.8.773
Nguyen, Ninh T. ; Longoria, Mario ; Welbourne, Susan ; Sabio, Allen ; Wilson, Samuel E. ; Goodnight, James E. ; Danto, Lawrence A. ; Curet, Myriam ; McConnell, Donald. / Glycolide copolymer staple-line reinforcement reduces staple site bleeding during laparoscopic gastric bypass : A prospective randomized trial. In: Archives of Surgery. 2005 ; Vol. 140, No. 8. pp. 773-778.
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abstract = "Hypothesis: The use of staple-line reinforcement sleeves during laparoscopic gastric bypass reduces staple-line bleeding, which may translate into a reduction in the rate of gastrointestinal hemorrhage. Design: Prospective randomized trial. Setting: University hospital. Patients and Interventions: Thirty-four patients undergoing laparoscopic gastric bypass were randomly assigned to receive either no reinforcement (control group, n=17) or reinforcement of the staple line with glycolic copolymer sleeves (treatment group, n=17). Main Outcome Measures: Demographic data, the number of stapler loads used, the number of staple-line bleeding sites, the amount of blood loss, the length of time required to obtain hemostasis of the staple lines, operative time, intraoperative and postoperative complications, and serial hemoglobin levels. Results: The mean number of stapler loads used was similar between groups. The mean number of staple-line bleeding sites was significantly fewer in the treatment group for division of gastric tissue (0.4 vs 2.5 bleeding sites), jejunal tissue (0.1 vs 0.6 bleeding site), and mesenteric tissue (0 vs 0.8 bleeding site). The mean blood loss was lower in the treatment group (84 vs 129 mL). Staple misfire occurred in 1 (0.7{\%}) of 143 stapler loads used in the treatment group compared with 0 (0{\%}) of 138 stapler loads used in the control group. The time to obtain stapleline hemostasis was shorter in the treatment group (1.2 vs 10.1 minutes). The total operative time was similar between groups. There was no mortality or postoperative leaks. One patient in the control group had postoperative gastrointestinal hemorrhage requiring blood transfusion and reoperation. There was no significant difference in the mean hemoglobin level between groups on the first postoperative day. Conclusions: The use of glycolide copolymer stapleline reinforcement sleeves in patients undergoing laparoscopic gastric bypass is safe and significantly reduces staple-line bleeding sites and may reduce the incidence of gastrointestinal hemorrhage.",
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AU - Sabio, Allen

AU - Wilson, Samuel E.

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AU - Curet, Myriam

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N2 - Hypothesis: The use of staple-line reinforcement sleeves during laparoscopic gastric bypass reduces staple-line bleeding, which may translate into a reduction in the rate of gastrointestinal hemorrhage. Design: Prospective randomized trial. Setting: University hospital. Patients and Interventions: Thirty-four patients undergoing laparoscopic gastric bypass were randomly assigned to receive either no reinforcement (control group, n=17) or reinforcement of the staple line with glycolic copolymer sleeves (treatment group, n=17). Main Outcome Measures: Demographic data, the number of stapler loads used, the number of staple-line bleeding sites, the amount of blood loss, the length of time required to obtain hemostasis of the staple lines, operative time, intraoperative and postoperative complications, and serial hemoglobin levels. Results: The mean number of stapler loads used was similar between groups. The mean number of staple-line bleeding sites was significantly fewer in the treatment group for division of gastric tissue (0.4 vs 2.5 bleeding sites), jejunal tissue (0.1 vs 0.6 bleeding site), and mesenteric tissue (0 vs 0.8 bleeding site). The mean blood loss was lower in the treatment group (84 vs 129 mL). Staple misfire occurred in 1 (0.7%) of 143 stapler loads used in the treatment group compared with 0 (0%) of 138 stapler loads used in the control group. The time to obtain stapleline hemostasis was shorter in the treatment group (1.2 vs 10.1 minutes). The total operative time was similar between groups. There was no mortality or postoperative leaks. One patient in the control group had postoperative gastrointestinal hemorrhage requiring blood transfusion and reoperation. There was no significant difference in the mean hemoglobin level between groups on the first postoperative day. Conclusions: The use of glycolide copolymer stapleline reinforcement sleeves in patients undergoing laparoscopic gastric bypass is safe and significantly reduces staple-line bleeding sites and may reduce the incidence of gastrointestinal hemorrhage.

AB - Hypothesis: The use of staple-line reinforcement sleeves during laparoscopic gastric bypass reduces staple-line bleeding, which may translate into a reduction in the rate of gastrointestinal hemorrhage. Design: Prospective randomized trial. Setting: University hospital. Patients and Interventions: Thirty-four patients undergoing laparoscopic gastric bypass were randomly assigned to receive either no reinforcement (control group, n=17) or reinforcement of the staple line with glycolic copolymer sleeves (treatment group, n=17). Main Outcome Measures: Demographic data, the number of stapler loads used, the number of staple-line bleeding sites, the amount of blood loss, the length of time required to obtain hemostasis of the staple lines, operative time, intraoperative and postoperative complications, and serial hemoglobin levels. Results: The mean number of stapler loads used was similar between groups. The mean number of staple-line bleeding sites was significantly fewer in the treatment group for division of gastric tissue (0.4 vs 2.5 bleeding sites), jejunal tissue (0.1 vs 0.6 bleeding site), and mesenteric tissue (0 vs 0.8 bleeding site). The mean blood loss was lower in the treatment group (84 vs 129 mL). Staple misfire occurred in 1 (0.7%) of 143 stapler loads used in the treatment group compared with 0 (0%) of 138 stapler loads used in the control group. The time to obtain stapleline hemostasis was shorter in the treatment group (1.2 vs 10.1 minutes). The total operative time was similar between groups. There was no mortality or postoperative leaks. One patient in the control group had postoperative gastrointestinal hemorrhage requiring blood transfusion and reoperation. There was no significant difference in the mean hemoglobin level between groups on the first postoperative day. Conclusions: The use of glycolide copolymer stapleline reinforcement sleeves in patients undergoing laparoscopic gastric bypass is safe and significantly reduces staple-line bleeding sites and may reduce the incidence of gastrointestinal hemorrhage.

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