Global Initiative on Obstructive Lung Disease (GOLD) classification of lung disease and mortality

Findings from the Atherosclerosis Risk in Communities (ARIC) study

David M. Mannino, Dennis E. Doherty, A (Sonia) Buist

Research output: Contribution to journalArticle

227 Citations (Scopus)

Abstract

Objective: To determine whether a modified Global Initiative on Obstructive Lung Diseases (GOLD) classification of chronic obstructive pulmonary disease (COPD) predicts mortality in a cohort of subjects followed for up to 11 years. Methods: We analyzed data from 15,759 adult participants, aged 43-66 years at baseline, in the Atherosclerosis Risk in Communities (ARIC) study. All baseline and follow-up data were available for 15,440 (97.9%) of the initial participants. We classified subjects using a modification of the GOLD criteria for COPD (prebronchodilator forced expiratory volume in 1 s (FEV1) stratification of disease severity), and added a "restricted" category (FEV1/FVC>70% and FVC

Original languageEnglish (US)
Pages (from-to)115-122
Number of pages8
JournalRespiratory Medicine
Volume100
Issue number1
DOIs
StatePublished - Jan 2006

Fingerprint

Obstructive Lung Diseases
Forced Expiratory Volume
Chronic Obstructive Pulmonary Disease
Lung Diseases
Atherosclerosis
Mortality

Keywords

  • Cohort study
  • COPD
  • GOLD classification
  • Lung function
  • Mortality
  • Smoking

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Global Initiative on Obstructive Lung Disease (GOLD) classification of lung disease and mortality : Findings from the Atherosclerosis Risk in Communities (ARIC) study. / Mannino, David M.; Doherty, Dennis E.; Buist, A (Sonia).

In: Respiratory Medicine, Vol. 100, No. 1, 01.2006, p. 115-122.

Research output: Contribution to journalArticle

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