TY - JOUR
T1 - Genetics of Personality Disorders
T2 - Perspectives From Personality and Psychopathology Research
AU - Nigg, Joel T.
AU - Goldsmith, H. Hill
PY - 1994/5
Y1 - 1994/5
N2 - Although the field is young, studies pertinent to genetic hypotheses have accumulated for several personality disorders. Genetic links to personality disorders from the domains of normal personality and Axis I disorders are reviewed. Evidence of a link to schizophrenia is clearest for schizotypal and less conclusive for paranoid and schizoid personality disorders. A genetic association between borderline personality disorder and affective disorders has not been clearly supported, but there may be a subtype genetically linked to affective disorders. Evidence of genetic influence is mixed for obsessive-compulsive personality disorder. In general, greater attention to dimensional phenotypic measures and multivariate designs can yield more definitive answers regarding the correct subtyping and probable etiology of personality disorders.
AB - Although the field is young, studies pertinent to genetic hypotheses have accumulated for several personality disorders. Genetic links to personality disorders from the domains of normal personality and Axis I disorders are reviewed. Evidence of a link to schizophrenia is clearest for schizotypal and less conclusive for paranoid and schizoid personality disorders. A genetic association between borderline personality disorder and affective disorders has not been clearly supported, but there may be a subtype genetically linked to affective disorders. Evidence of genetic influence is mixed for obsessive-compulsive personality disorder. In general, greater attention to dimensional phenotypic measures and multivariate designs can yield more definitive answers regarding the correct subtyping and probable etiology of personality disorders.
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U2 - 10.1037/0033-2909.115.3.346
DO - 10.1037/0033-2909.115.3.346
M3 - Article
C2 - 8016285
AN - SCOPUS:0028436350
VL - 115
SP - 346
EP - 380
JO - Psychological Bulletin
JF - Psychological Bulletin
SN - 0033-2909
IS - 3
ER -