Generating subsurface acoustic waves in indocyanine green stained elastin biomaterial using a Q-switched laser

John A. Viator; Steve L. Jacques; Scott A. Prahl

doi:10.1117/12.308154

Generating subsurface acoustic waves in indocyanine green stained elastin biomaterial using a Q-switched laser

John A. Viator, Steve L. Jacques, Scott A. Prahl

Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

A Q-switched frequency-doubled Nd-YAG laser coupled to an optical parametric oscillator generated 4.75 ns 800 nm laser pulses to create a subsurface acoustic wave in planar indocyanine green gel samples and flat segments of elastin biomaterial stained with indocyanine green. The acoustic waves traveled through the target and were detected by a piezoelectric transducer. The waveforms were converted to measurements of pressure (and temperature) as a function of depth in the material. An algorithm was developed and applied to the acoustic signals to extract information about the the absorption coefficient as a function of depth in the samples.

Original language	English (US)
Pages (from-to)	104-111
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3254
DOIs	https://doi.org/10.1117/12.308154
State	Published - 1998
Event	Laser-Tissue Interaction IX - San Jose, CA, United States Duration: Jan 26 1998 → Jan 28 1998

Keywords

Absorption coefficient
Depth profiling
Photoacoustic imaging
Photothermal imaging

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.308154

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title = "Generating subsurface acoustic waves in indocyanine green stained elastin biomaterial using a Q-switched laser",

abstract = "A Q-switched frequency-doubled Nd-YAG laser coupled to an optical parametric oscillator generated 4.75 ns 800 nm laser pulses to create a subsurface acoustic wave in planar indocyanine green gel samples and flat segments of elastin biomaterial stained with indocyanine green. The acoustic waves traveled through the target and were detected by a piezoelectric transducer. The waveforms were converted to measurements of pressure (and temperature) as a function of depth in the material. An algorithm was developed and applied to the acoustic signals to extract information about the the absorption coefficient as a function of depth in the samples.",

keywords = "Absorption coefficient, Depth profiling, Photoacoustic imaging, Photothermal imaging",

author = "Viator, {John A.} and Jacques, {Steve L.} and Prahl, {Scott A.}",

year = "1998",

doi = "10.1117/12.308154",

language = "English (US)",

volume = "3254",

pages = "104--111",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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note = "Laser-Tissue Interaction IX ; Conference date: 26-01-1998 Through 28-01-1998",

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T1 - Generating subsurface acoustic waves in indocyanine green stained elastin biomaterial using a Q-switched laser

AU - Viator, John A.

AU - Jacques, Steve L.

AU - Prahl, Scott A.

PY - 1998

Y1 - 1998

N2 - A Q-switched frequency-doubled Nd-YAG laser coupled to an optical parametric oscillator generated 4.75 ns 800 nm laser pulses to create a subsurface acoustic wave in planar indocyanine green gel samples and flat segments of elastin biomaterial stained with indocyanine green. The acoustic waves traveled through the target and were detected by a piezoelectric transducer. The waveforms were converted to measurements of pressure (and temperature) as a function of depth in the material. An algorithm was developed and applied to the acoustic signals to extract information about the the absorption coefficient as a function of depth in the samples.

AB - A Q-switched frequency-doubled Nd-YAG laser coupled to an optical parametric oscillator generated 4.75 ns 800 nm laser pulses to create a subsurface acoustic wave in planar indocyanine green gel samples and flat segments of elastin biomaterial stained with indocyanine green. The acoustic waves traveled through the target and were detected by a piezoelectric transducer. The waveforms were converted to measurements of pressure (and temperature) as a function of depth in the material. An algorithm was developed and applied to the acoustic signals to extract information about the the absorption coefficient as a function of depth in the samples.

KW - Absorption coefficient

KW - Depth profiling

KW - Photoacoustic imaging

KW - Photothermal imaging

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AN - SCOPUS:0032225141

SN - 0277-786X

VL - 3254

SP - 104

EP - 111

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Laser-Tissue Interaction IX

Y2 - 26 January 1998 through 28 January 1998

ER -

Generating subsurface acoustic waves in indocyanine green stained elastin biomaterial using a Q-switched laser

Abstract

Keywords

ASJC Scopus subject areas

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