Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1)

Michael Litt, D. LaMorticella, C. T. Bond, John Adelman

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Small-conductance, calcium-activated potassium channels contribute to the afterhyperpolarization in central neurons and other cell types. Because these channels regulate neuronal excitability, defects in their genes could cause excitability disorders. The human cDNA encoding one such channel, SK1 (KCNN1), was recently cloned. Here we describe the gene structure of KCNN1 and its localization by radiation hybrid mapping to chromosome 19p13.1.

Original languageEnglish (US)
Pages (from-to)70-73
Number of pages4
JournalCytogenetics and Cell Genetics
Volume86
Issue number1
StatePublished - 1999

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Small-Conductance Calcium-Activated Potassium Channels
Chromosome Mapping
Radiation Hybrid Mapping
Genes
Complementary DNA
Chromosomes
Neurons

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

Cite this

Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1). / Litt, Michael; LaMorticella, D.; Bond, C. T.; Adelman, John.

In: Cytogenetics and Cell Genetics, Vol. 86, No. 1, 1999, p. 70-73.

Research output: Contribution to journalArticle

Litt, Michael ; LaMorticella, D. ; Bond, C. T. ; Adelman, John. / Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1). In: Cytogenetics and Cell Genetics. 1999 ; Vol. 86, No. 1. pp. 70-73.
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