First example of a molecularly imprinted polymer incorporating a difunctionalized alloxazine flavin isomer

Andrew J. Robak, Bruce Branchaud

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

High-quality alloxazine (a flavin isomer) imprinted polymers have been made for the first time. A molecularly imprinted polymer (MIP) for the N1,N3-di-functionalized alloxazine template 2 was made. The MIP prepared for 2 exhibited excellent, highly selective molecular recognition for template 2, as determined by HPLC analysis using columns prepared with the MIP. This has also demonstrated that the core flavin structure can survive the imprinting process.

Original languageEnglish (US)
Pages (from-to)5651-5654
Number of pages4
JournalTetrahedron Letters
Volume46
Issue number34
DOIs
StatePublished - Aug 22 2005
Externally publishedYes

Fingerprint

Isomers
Polymers
Molecular recognition
High Pressure Liquid Chromatography
4,6-dinitro-o-cresol
isoalloxazine

Keywords

  • Alloxazine
  • Enzyme mimetic
  • Flavin
  • Molecularly imprinted polymer
  • Redox catalyst

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

First example of a molecularly imprinted polymer incorporating a difunctionalized alloxazine flavin isomer. / Robak, Andrew J.; Branchaud, Bruce.

In: Tetrahedron Letters, Vol. 46, No. 34, 22.08.2005, p. 5651-5654.

Research output: Contribution to journalArticle

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