Fever and Neutropenia in Pediatric Patients with Cancer

Garth Meckler, Susan Lindemulder

Research output: Contribution to journalReview article

41 Scopus citations

Abstract

Aggressive treatment of childhood cancers including systemic antineoplastic and radiation therapy has secondary effects on a variety of normal cells including hematopoietic elements of the bone marrow, often causing neutropenia. Neutropenia increases the risk for serious infection and is associated with significant morbidity and mortality. The approach to the treatment of the febrile neutropenic pediatric patient has evolved considerably because high- and low-risk criteria have been defined and broad-spectrum antibiotics developed. This article reviews the concepts involved in the evaluation and management of febrile, neutropenic, pediatric cancer patients.

Original languageEnglish (US)
Pages (from-to)525-544
Number of pages20
JournalEmergency Medicine Clinics of North America
Volume27
Issue number3
DOIs
StatePublished - Aug 2009

Keywords

  • Fever
  • Management
  • Neutropenia
  • Oncology
  • Pediatric

ASJC Scopus subject areas

  • Emergency Medicine

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