TY - JOUR
T1 - Feasibility and acceptability of a real-time adherence device among HIV-positive IDU patients in China
AU - Bachman Desilva, Mary
AU - Gifford, Allen L.
AU - Keyi, Xu
AU - Li, Zhong
AU - Feng, Cheng
AU - Brooks, Mohamad
AU - Harrold, Mark
AU - Yueying, Hu
AU - Gill, Christopher J.
AU - Wubin, Xie
AU - Vian, Taryn
AU - Haberer, Jessica
AU - Bangsberg, David
AU - Sabin, Lora
PY - 2013
Y1 - 2013
N2 - We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. "Wisepill" uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.
AB - We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. "Wisepill" uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.
UR - http://www.scopus.com/inward/record.url?scp=84881497674&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881497674&partnerID=8YFLogxK
U2 - 10.1155/2013/957862
DO - 10.1155/2013/957862
M3 - Article
C2 - 23956851
AN - SCOPUS:84881497674
SN - 2090-1240
VL - 2013
JO - AIDS Research and Treatment
JF - AIDS Research and Treatment
M1 - 957862
ER -