Fatal Clostridial necrotizing enterocolitis in a term infant with gastroschisis

Kevin M. Riggle, Jessica L. Davis, George T. Drugas, Kimberly J. Riehle

Research output: Contribution to journalArticle

Abstract

Necrotizing enterocolitis (NEC) is most often a disease of preterm infants, but can develop in full term infants with gastroschisis. The latter cases typically present later and have a milder clinical course; we present the first case of fatal Clostridium perfringes-associated NEC in a full term infant with gastroschisis. Our case highlights the need for a high index of clinical suspicion for Clostridial NEC when there is rapid progression of disease and/or evidence of hemolysis. When Clostridial NEC is suspected, we recommend treatment with penicillin G and clindamycin, as well as prompt, aggressive surgical intervention.

Original languageEnglish (US)
Pages (from-to)29-31
Number of pages3
JournalJournal of Pediatric Surgery Case Reports
Volume14
DOIs
StatePublished - Nov 1 2016

Keywords

  • C. perfringes
  • Gastroschisis
  • NEC

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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