Factors Associated with Success in First-Time Trabeculectomy for Patients at Low Risk of Failure with Chronic Open-Angle Glaucoma

Lorna (Beth) Edmunds, Catey V. Bunce, John R. Thompson, John F. Salmon, Richard P. Wormald

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Purpose: To examine the relationships between study factors and trabeculectomy outcome in a representative sample of United Kingdom ophthalmology surgeons and patients. Design: Cross-sectional observational study by questionnaire. Participants: All ophthalmic surgeons performing trabeculectomy in the National Health Service were invited to select their 4 most recent consecutive trabeculectomy cases satisfying study eligibility criteria before June 1996. Three hundred eighty-two surgeons supplied baseline data for 1450 patients and 1-year follow-up data for 1240 (85.3%) patients. All patients had undergone first-time trabeculectomy for chronic open-angle glaucoma. Methods: Data were collected by self-administered questionnaires at baseline and 6 and 12 months postoperatively. Univariate analysis of the relationships between study factors and success was performed by chi-square test (categorical variables) and Student's t or Mann-Whitney U tests (continuous variables). Multiple logistic regression modeling of explanatory variables significant at a P value of ≤0.1 was then performed. Main Outcome Measure: Trabeculectomy success, defined as a final intraocular pressure (IOP) less than two thirds of the preoperative IOP, excluding patients on antiglaucoma medications. Results: After multiple logistic regression modeling, diabetes (odds ratio [OR] = 0.485, 95% confidence interval [CI] = 0.271-0.868, P = 0.015), superior rectus traction suture (OR = 0.580, 95% CI = 0.348-0.959, P = 0.034), subconjunctival anesthetic (OR = 0.172, 95% CI = 0.065-0.459, P

Original languageEnglish (US)
Pages (from-to)97-103
Number of pages7
JournalOphthalmology
Volume111
Issue number1
DOIs
StatePublished - Jan 2004
Externally publishedYes

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Trabeculectomy
Open Angle Glaucoma
Odds Ratio
Confidence Intervals
Intraocular Pressure
Logistic Models
National Health Programs
Traction
Ophthalmology
Chi-Square Distribution
Nonparametric Statistics
Sutures
Observational Studies
Anesthetics
Cross-Sectional Studies
Outcome Assessment (Health Care)
Students
Surgeons

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Factors Associated with Success in First-Time Trabeculectomy for Patients at Low Risk of Failure with Chronic Open-Angle Glaucoma. / Edmunds, Lorna (Beth); Bunce, Catey V.; Thompson, John R.; Salmon, John F.; Wormald, Richard P.

In: Ophthalmology, Vol. 111, No. 1, 01.2004, p. 97-103.

Research output: Contribution to journalArticle

Edmunds, Lorna (Beth) ; Bunce, Catey V. ; Thompson, John R. ; Salmon, John F. ; Wormald, Richard P. / Factors Associated with Success in First-Time Trabeculectomy for Patients at Low Risk of Failure with Chronic Open-Angle Glaucoma. In: Ophthalmology. 2004 ; Vol. 111, No. 1. pp. 97-103.
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