Extremity osteosarcoma in childhood: Prognostic value of radiologic imaging

Janet A. Lawrence, Paul S. Babyn, Helen S L Chan, Paul S. Thorner, Gaylene E. Fron, Joseph (Ivan) Krajbich

Research output: Contribution to journalArticle

46 Scopus citations


PURPOSE: To evaluate previously described radiologic prognostic factors in extremity osteosarcoma. MATERIALS AND METHODS: In 47 pediatric patients, available images were evaluated for seven prognostic factors at diagnosis and seven additional factors after preoperative chemotherapy. These factors were correlated with histopathologic response and clinical outcome. The association of histopathologic response and outcome was also evaluated. RESULTS: Metastases at presentation and a >20-cm-diameter soft-tissue mass were predictive of a poor outcome but occurred in few patients. Factors most predictive of

Original languageEnglish (US)
Pages (from-to)43-47
Number of pages5
Issue number1
Publication statusPublished - Oct 1993
Externally publishedYes



  • Bone neoplasms, 40.3221
  • Extremities, neoplasms, 40.3221
  • Neoplasms, in infants and children
  • Osteosarcoma, 40.3221

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Lawrence, J. A., Babyn, P. S., Chan, H. S. L., Thorner, P. S., Fron, G. E., & Krajbich, J. I. (1993). Extremity osteosarcoma in childhood: Prognostic value of radiologic imaging. Radiology, 189(1), 43-47.