TY - GEN
T1 - Extracting scattering coefficient and anisotropy factor of tissue using optical coherence tomography
AU - Choudhury, Niloy
AU - Jacques, Steven L.
PY - 2012
Y1 - 2012
N2 - Determination of tissue optical properties is important as it will lead to better design of optical diagnostic tools, improvement in laser therapy, photo dynamic therapy dosimetry, drug pharmacokinetics, etc. We have developed a theoretical model for OCT signal using Monte Carlo simulation that allows us to fit values extracted from the OCT signal, namely, reflectance, ρ, and the total optical attenuation coefficient, μt, to obtain optical properties of tissue (scattering coefficient, μs, and anisotropy factor, g). Using this method we have extracted optical properties of different tissue types, e.g., skin, muscle, liver, and brain of mouse.
AB - Determination of tissue optical properties is important as it will lead to better design of optical diagnostic tools, improvement in laser therapy, photo dynamic therapy dosimetry, drug pharmacokinetics, etc. We have developed a theoretical model for OCT signal using Monte Carlo simulation that allows us to fit values extracted from the OCT signal, namely, reflectance, ρ, and the total optical attenuation coefficient, μt, to obtain optical properties of tissue (scattering coefficient, μs, and anisotropy factor, g). Using this method we have extracted optical properties of different tissue types, e.g., skin, muscle, liver, and brain of mouse.
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U2 - 10.1117/12.907401
DO - 10.1117/12.907401
M3 - Conference contribution
AN - SCOPUS:84859015250
SN - 9780819488640
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Interactions with Tissue and Cells XXIII
T2 - Optical Interactions with Tissue and Cells XXIII
Y2 - 23 January 2012 through 25 January 2012
ER -