Exocytosis and its control at the synapse

Paul Thomas; Wolfhard Almers

doi:10.1016/0959-4388(92)90120-A

Exocytosis and its control at the synapse

Paul Thomas, Wolfhard Almers

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Several new approaches have given fresh insight into the mechanism and control of exocytosis. Electrophysiological and morphological studies show that many or all of the intramembrane particles at presynaptic active zones are voltage-gated Ca²⁺ channels. The sensitivity and time resolution of voltammetry allow the time course with which a single vesicle releases transmitter to be studied. Membrane proteins of the cell surface and synaptic vesicles have been shown to interact, and may join to form the fusion-pore complex.

Original language	English (US)
Pages (from-to)	308-311
Number of pages	4
Journal	Current Opinion in Neurobiology
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/0959-4388(92)90120-A
State	Published - Jun 1992
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

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10.1016/0959-4388(92)90120-A

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abstract = "Several new approaches have given fresh insight into the mechanism and control of exocytosis. Electrophysiological and morphological studies show that many or all of the intramembrane particles at presynaptic active zones are voltage-gated Ca2+ channels. The sensitivity and time resolution of voltammetry allow the time course with which a single vesicle releases transmitter to be studied. Membrane proteins of the cell surface and synaptic vesicles have been shown to interact, and may join to form the fusion-pore complex.",

author = "Paul Thomas and Wolfhard Almers",

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AB - Several new approaches have given fresh insight into the mechanism and control of exocytosis. Electrophysiological and morphological studies show that many or all of the intramembrane particles at presynaptic active zones are voltage-gated Ca2+ channels. The sensitivity and time resolution of voltammetry allow the time course with which a single vesicle releases transmitter to be studied. Membrane proteins of the cell surface and synaptic vesicles have been shown to interact, and may join to form the fusion-pore complex.

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Exocytosis and its control at the synapse

Abstract

ASJC Scopus subject areas

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