Exocytosis and its control at the synapse

Paul Thomas, Wolfhard Almers

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Several new approaches have given fresh insight into the mechanism and control of exocytosis. Electrophysiological and morphological studies show that many or all of the intramembrane particles at presynaptic active zones are voltage-gated Ca2+ channels. The sensitivity and time resolution of voltammetry allow the time course with which a single vesicle releases transmitter to be studied. Membrane proteins of the cell surface and synaptic vesicles have been shown to interact, and may join to form the fusion-pore complex.

Original languageEnglish (US)
Pages (from-to)308-311
Number of pages4
JournalCurrent Opinion in Neurobiology
Volume2
Issue number3
DOIs
StatePublished - Jun 1992

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ASJC Scopus subject areas

  • Neuroscience(all)

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