Evolution in action

Thomas S. Scanlan, Ralph C. Reid

Research output: Contribution to journalShort surveypeer-review

42 Scopus citations


The α β barrel enzyme phosphotriesterase from soil bacteria appears to have evolved the ability to hydrolyze the insecticide paraoxon at the diffusion limit in only a few decades. A newly-identified open reading frame from Escherichia coli may offer a clue to its origins.

Original languageEnglish (US)
Pages (from-to)71-75
Number of pages5
JournalChemistry and Biology
Issue number2
StatePublished - Feb 1995
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry


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