Evaluation of diffuse liver steatosis by ultrasound, computed tomography, and magnetic resonance imaging: which modality is best?

Aliya Qayyum, Daryl M. Chen, Richard S. Breiman, Antonio C. Westphalen, Benjamin M. Yeh, Kirk D. Jones, Ying Lu, Fergus V. Coakley, Peter W. Callen

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

Purpose: To compare ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) determination of diffuse liver steatosis. Materials and methods: Quantification of liver steatosis on ultrasound, CT, and MRI was correlated with histopathology in 67 patients. Results: Opposed-phase MRI demonstrated the highest correlation with steatosis (0.68 and 0.69, P<.01; intraclass correlation coefficient, 0.93). Spearman's correlation (and intraclass correlation) coefficients were lowest for ultrasound [0.54, 0.33 (0.40)] and enhanced CT [0.33, 0.39 (0.97)]. Conclusion: Opposed-phase MRI demonstrated best overall performance for determining steatosis.

Original languageEnglish (US)
Pages (from-to)110-115
Number of pages6
JournalClinical Imaging
Volume33
Issue number2
DOIs
StatePublished - Mar 1 2009

Keywords

  • Computed tomography (CT)
  • Liver, steatosis
  • Magnetic resonance imaging (MRI)
  • Ultrasound (US)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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