Enantioselective addition of diethylzinc to aldehydes catalyzed by a β-amino alcohol derived from (+)-3-carene

Sudhir N. Joshi, Sanjay V. Malhotra

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

A (+)-3-carene derived aminoalcohol was successfully used as a chiral ligand in the catalytic enantioselective diethylzinc addition to various aldehydes. Very high enantiomeric excess (up 98% in 1-(2-methoxyphenyl)-1-propanol) was obtained. A plausible mechanism has been suggested for the observed enantioselectivity.

Original languageEnglish (US)
Pages (from-to)1763-1766
Number of pages4
JournalTetrahedron Asymmetry
Volume14
Issue number13
DOIs
StatePublished - Jul 4 2003
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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