Elevated umbilical cord blood leukocyte cyclic adenosine monophosphate-phosphodiesterase activity in children with atopic parents

N. S. Heskel, S. C. Chan, M. L. Thiel, S. R. Stevens, L. S. Casperson, Jon Hanifin

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

We found cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) activity to be significantly elevated in the umbilical cord blood mononuclear leukocytes of forty-two children with one atopic parent (3.2 ± 0.3) and in eighteen children with two atopic parents (4.2 ± 0.7) as compared to twenty-two children with two nonatopic parents (1.9 ± 0.2) (p

Original languageEnglish (US)
Pages (from-to)422-426
Number of pages5
JournalJournal of the American Academy of Dermatology
Volume11
Issue number3
DOIs
StatePublished - 1984

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Phosphoric Diester Hydrolases
Fetal Blood
Cyclic AMP
Leukocytes
Parents
Mononuclear Leukocytes

ASJC Scopus subject areas

  • Dermatology

Cite this

Elevated umbilical cord blood leukocyte cyclic adenosine monophosphate-phosphodiesterase activity in children with atopic parents. / Heskel, N. S.; Chan, S. C.; Thiel, M. L.; Stevens, S. R.; Casperson, L. S.; Hanifin, Jon.

In: Journal of the American Academy of Dermatology, Vol. 11, No. 3, 1984, p. 422-426.

Research output: Contribution to journalArticle

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