Electron microscope heteroduplex studies of sequence relationships among plasmids of the W incompatibility group

A. Patricia Gorai, Fred Heffron, Stanley Falkow, R. W. Hedges, Naomi Datta

    Research output: Contribution to journalArticle

    22 Scopus citations

    Abstract

    Several plasmids of the W incompatibility group were examined by electron microscope heteroduplex analysis. They were all conjugative plasmids of about 20 × 106 daltons even though isolated from different bacterial species in different parts of the world. One stretch of DNA of about 13 × 106 daltons was common to all W plasmids. This region included genes associated with plasmid transfer. The various drug resistance genes, including a known transposition sequence, were clustered in a single region of the W plasmid chromosome.

    Original languageEnglish (US)
    Pages (from-to)485-492
    Number of pages8
    JournalPlasmid
    Volume2
    Issue number3
    DOIs
    StatePublished - Jul 1979

    ASJC Scopus subject areas

    • Molecular Biology

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