Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing

Phillip D K Lee, Darrell M. Wilson, Lois Rountree, Raymond L. Hintz, Ronald (Ron) Rosenfeld

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Clinical testing of growth hormone (GH) sufficiency is a controversial area in endocrinology. Due to the episodic nature of endogenous GH secretion, diagnosis of GH deficiency has been defined as a failure to achieve normal GH levels in response to at least two stimuli. This testing is associated with significant patient morbidity and cost. We analyzed our experience over a 4-y period to determine whether clinical or biochemical variables could be used to predict the results of a specific GH testing procedure. Of 180 cases analyzed (67% male, mean age 8.89 ± 4.39 y, range neonate-16 y), eight cases had incomplete GH testing results. Of the remaining 172, 19 were GH deficient (GH level

Original languageEnglish (US)
Pages (from-to)45-51
Number of pages7
JournalPediatric Research
Volume27
Issue number1
StatePublished - 1990
Externally publishedYes

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Insulin-Like Growth Factor I
Growth Hormone
Endocrinology
Newborn Infant
Morbidity
Costs and Cost Analysis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Lee, P. D. K., Wilson, D. M., Rountree, L., Hintz, R. L., & Rosenfeld, R. R. (1990). Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing. Pediatric Research, 27(1), 45-51.

Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing. / Lee, Phillip D K; Wilson, Darrell M.; Rountree, Lois; Hintz, Raymond L.; Rosenfeld, Ronald (Ron).

In: Pediatric Research, Vol. 27, No. 1, 1990, p. 45-51.

Research output: Contribution to journalArticle

Lee, PDK, Wilson, DM, Rountree, L, Hintz, RL & Rosenfeld, RR 1990, 'Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing', Pediatric Research, vol. 27, no. 1, pp. 45-51.
Lee, Phillip D K ; Wilson, Darrell M. ; Rountree, Lois ; Hintz, Raymond L. ; Rosenfeld, Ronald (Ron). / Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing. In: Pediatric Research. 1990 ; Vol. 27, No. 1. pp. 45-51.
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