Effects of imipramine on the sleep-dream cycle: An EEG study in boys

Edward R. Ritvo; Edward M. Ornitz; Steven La Franchi; Richard D. Walter

doi:10.1016/0013-4694(67)90174-5

Effects of imipramine on the sleep-dream cycle: An EEG study in boys

Edward R. Ritvo, Edward M. Ornitz, Steven La Franchi, Richard D. Walter

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The effect of imipramine on the sleep cycle in seven boys, aged 9-11, was studied by a single blind technique recording EEG and EOM. It was demonstrated that imipramine influences the sleep-dream cycle in the following manner: (1) the percentage of time spent in REM state sleep was decreased; (2) the percentage of time spent in Stage 2 sleep was increased; (3) a longer latency from the onset of sleep to the first REM epoch was produced. No difference was observed between the amounts of time spent in combined Stages 3-4 sleep or in the over-all length of time spent asleep in the laboratory.

Original language	English (US)
Pages (from-to)	465-468
Number of pages	4
Journal	Electroencephalography and Clinical Neurophysiology
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/0013-4694(67)90174-5
State	Published - May 1967
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience
Clinical Neurology

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abstract = "The effect of imipramine on the sleep cycle in seven boys, aged 9-11, was studied by a single blind technique recording EEG and EOM. It was demonstrated that imipramine influences the sleep-dream cycle in the following manner: (1) the percentage of time spent in REM state sleep was decreased; (2) the percentage of time spent in Stage 2 sleep was increased; (3) a longer latency from the onset of sleep to the first REM epoch was produced. No difference was observed between the amounts of time spent in combined Stages 3-4 sleep or in the over-all length of time spent asleep in the laboratory.",

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AU - Walter, Richard D.

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AB - The effect of imipramine on the sleep cycle in seven boys, aged 9-11, was studied by a single blind technique recording EEG and EOM. It was demonstrated that imipramine influences the sleep-dream cycle in the following manner: (1) the percentage of time spent in REM state sleep was decreased; (2) the percentage of time spent in Stage 2 sleep was increased; (3) a longer latency from the onset of sleep to the first REM epoch was produced. No difference was observed between the amounts of time spent in combined Stages 3-4 sleep or in the over-all length of time spent asleep in the laboratory.

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Effects of imipramine on the sleep-dream cycle: An EEG study in boys

Abstract

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