The effect of imipramine on the sleep cycle in seven boys, aged 9-11, was studied by a single blind technique recording EEG and EOM. It was demonstrated that imipramine influences the sleep-dream cycle in the following manner: (1) the percentage of time spent in REM state sleep was decreased; (2) the percentage of time spent in Stage 2 sleep was increased; (3) a longer latency from the onset of sleep to the first REM epoch was produced. No difference was observed between the amounts of time spent in combined Stages 3-4 sleep or in the over-all length of time spent asleep in the laboratory.
|Original language||English (US)|
|Number of pages||4|
|Journal||Electroencephalography and Clinical Neurophysiology|
|State||Published - May 1967|
ASJC Scopus subject areas
- Clinical Neurology