Effect of pupil dilation on biometric measurements and intraocular lens power calculations in schoolchildren

Xiaogang Wang, Jing Dong, Maolong Tang, Xiaoliang Wang, Haitao Wang, Suhua Zhang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose To investigate the effect of pupil dilation on ocular biometric parameters and intraocular lens (IOL) power calculation in schoolchildren using the Lenstar LS 900. Methods One hundred forty eyes of 140 healthy schoolchildren were included in the analysis. Axial length (AL), central corneal thickness (CCT), aqueous depth (AD), anterior chamber depth (ACD), lens thickness (LT), flat keratometry (K), steep K, astigmatism, white-to-white (WTW), and iris/pupil barycenter distance were measured, before and after pupil dilation. Anterior segment length (ASL) was defined as the sum of ACD and LT, and lens position (LP) was defined as ACD plus half of the LT. The relative lens position (RLP) was defined as LP divided by AL. IOL power was calculated using the eight formulas (Hill-RBF, Barrett, Haigis, Hoffer Q, Holladay, Olsen, SRK II, and SRK/T) integrated in the Lenstar LS 900. Parameters before and after pupil dilation were compared. Results AL, AD, ACD, LT, ASL, LP, RLP, flat K, iris barycenter distance, pupil barycenter distance, and PD differed significantly after pupil dilation (P < 0.001 in all cases), as compared to before dilation. The Olsen formula demonstrated significant differences in the magnitude of astigmatism (P = 0.010) and IOL power (P = 0.003) after pupil dilation. Using the different formulas, 23.6–40.7% of participants had IOL power changes of more than 0.50 diopters, while 0.7–1.4% had IOL changes of more than 1.0 diopter after pupil dilation. Conclusions Dilated and undilated pupil size affected the Lenstar LS 900 measurement of some ocular biometric parameters, and pupil dilation led to IOL power changes exceeding 0.50 diopters with a high percentage (from 23.6% to 40.7%) in schoolchildren, which should be noticed in clinical practice.

Original languageEnglish (US)
Article numbere0203677
JournalPLoS One
Volume13
Issue number9
DOIs
StatePublished - Sep 1 2018

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Intraocular lenses
school children
Intraocular Lenses
Biometrics
Pupil
biometry
Lens
Dilatation
Lenses
Anterior Chamber
Astigmatism
Iris
iris (eyes)
eyes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Effect of pupil dilation on biometric measurements and intraocular lens power calculations in schoolchildren. / Wang, Xiaogang; Dong, Jing; Tang, Maolong; Wang, Xiaoliang; Wang, Haitao; Zhang, Suhua.

In: PLoS One, Vol. 13, No. 9, e0203677, 01.09.2018.

Research output: Contribution to journalArticle

Wang, Xiaogang ; Dong, Jing ; Tang, Maolong ; Wang, Xiaoliang ; Wang, Haitao ; Zhang, Suhua. / Effect of pupil dilation on biometric measurements and intraocular lens power calculations in schoolchildren. In: PLoS One. 2018 ; Vol. 13, No. 9.
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abstract = "Purpose To investigate the effect of pupil dilation on ocular biometric parameters and intraocular lens (IOL) power calculation in schoolchildren using the Lenstar LS 900. Methods One hundred forty eyes of 140 healthy schoolchildren were included in the analysis. Axial length (AL), central corneal thickness (CCT), aqueous depth (AD), anterior chamber depth (ACD), lens thickness (LT), flat keratometry (K), steep K, astigmatism, white-to-white (WTW), and iris/pupil barycenter distance were measured, before and after pupil dilation. Anterior segment length (ASL) was defined as the sum of ACD and LT, and lens position (LP) was defined as ACD plus half of the LT. The relative lens position (RLP) was defined as LP divided by AL. IOL power was calculated using the eight formulas (Hill-RBF, Barrett, Haigis, Hoffer Q, Holladay, Olsen, SRK II, and SRK/T) integrated in the Lenstar LS 900. Parameters before and after pupil dilation were compared. Results AL, AD, ACD, LT, ASL, LP, RLP, flat K, iris barycenter distance, pupil barycenter distance, and PD differed significantly after pupil dilation (P < 0.001 in all cases), as compared to before dilation. The Olsen formula demonstrated significant differences in the magnitude of astigmatism (P = 0.010) and IOL power (P = 0.003) after pupil dilation. Using the different formulas, 23.6–40.7{\%} of participants had IOL power changes of more than 0.50 diopters, while 0.7–1.4{\%} had IOL changes of more than 1.0 diopter after pupil dilation. Conclusions Dilated and undilated pupil size affected the Lenstar LS 900 measurement of some ocular biometric parameters, and pupil dilation led to IOL power changes exceeding 0.50 diopters with a high percentage (from 23.6{\%} to 40.7{\%}) in schoolchildren, which should be noticed in clinical practice.",
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