Effect of biopsy type on outcomes in the treatment of primary cutaneous melanoma

Jane K. Mills, Ian White, Brian Diggs, Jeanine Fortino, John Vetto

    Research output: Contribution to journalArticle

    28 Citations (Scopus)

    Abstract

    Background: Surgical excision remains the primary and only potentially curative treatment for melanoma. Although current guidelines recommend excisional biopsy as the technique of choice for evaluating lesions suspected of being primary melanomas, other biopsy types are commonly used. We sought to determine the impact of biopsy type (excisional, shave, or punch) on outcomes in melanoma. Methods: A prospectively collected, institutional review board-approved database of primary clinically node-negative melanomas (stages cT1-4N0) was reviewed to determine the impact of biopsy type on T-staging accuracy, wide local excision (WLE) area (cm2), sentinel lymph node biopsy (SLNB) identification rates and results, tumor recurrence, and patient survival. Results: Seven hundred nine patients were diagnosed by punch biopsy (23%), shave biopsy (34%), and excisional biopsy (43%). Shave biopsy results showed significantly more positive deep margins (P

    Original languageEnglish (US)
    Pages (from-to)585-590
    Number of pages6
    JournalAmerican Journal of Surgery
    Volume205
    Issue number5
    DOIs
    StatePublished - May 2013

    Fingerprint

    Melanoma
    Biopsy
    Skin
    Sentinel Lymph Node Biopsy
    Research Ethics Committees
    Databases
    Guidelines
    Recurrence
    Survival
    Neoplasms

    Keywords

    • Biopsy
    • Diagnosis
    • Melanoma
    • Survival
    • Wide local excision

    ASJC Scopus subject areas

    • Surgery

    Cite this

    Effect of biopsy type on outcomes in the treatment of primary cutaneous melanoma. / Mills, Jane K.; White, Ian; Diggs, Brian; Fortino, Jeanine; Vetto, John.

    In: American Journal of Surgery, Vol. 205, No. 5, 05.2013, p. 585-590.

    Research output: Contribution to journalArticle

    Mills, Jane K. ; White, Ian ; Diggs, Brian ; Fortino, Jeanine ; Vetto, John. / Effect of biopsy type on outcomes in the treatment of primary cutaneous melanoma. In: American Journal of Surgery. 2013 ; Vol. 205, No. 5. pp. 585-590.
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