Early Treatment in Emergency Department Patients with Acute Heart Failure: Does Time Matter?

Anna Marie Chang; Peter S. Pang; Javed Butler; Alan B. Storrow; Phillip D. Levy; Jo Ann Lindenfeld; Sean P. Collins

doi:10.1007/s11897-019-0419-y

Early Treatment in Emergency Department Patients with Acute Heart Failure: Does Time Matter?

Anna Marie Chang, Peter S. Pang, Javed Butler, Alan B. Storrow, Phillip D. Levy, Jo Ann Lindenfeld, Sean P. Collins

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Purpose of Review: Acute heart failure accounts for over one million hospital discharges annually. Current guidelines suggest treatments for AHF should begin “without delay” but this time interval has not been clearly defined. Recent Findings: Data suggest that certain treatments such as earlier treatment with diuretics and vasodilators may improve patient symptom relief, morbidity, and mortality. Secondary analyses of clinical trials of novel treatments under development have not shown similar results. Summary: The data are equivocal regarding the impact of early treatment in AHF on in-hospital and long-term morbidity and mortality. Improved clinical trial designs will help answer when and if “early” treatment should begin and whether it impacts short- and long-term outcomes in AHF.

Original language	English (US)
Pages (from-to)	12-20
Number of pages	9
Journal	Current heart failure reports
Volume	16
Issue number	1
DOIs	https://doi.org/10.1007/s11897-019-0419-y
State	Published - Feb 15 2019
Externally published	Yes

Keywords

Acute heart failure
Emergency medicine
Treatments for AHF

ASJC Scopus subject areas

Emergency Medicine
Cardiology and Cardiovascular Medicine
Physiology (medical)

Access to Document

10.1007/s11897-019-0419-y

Cite this

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title = "Early Treatment in Emergency Department Patients with Acute Heart Failure: Does Time Matter?",

abstract = "Purpose of Review: Acute heart failure accounts for over one million hospital discharges annually. Current guidelines suggest treatments for AHF should begin “without delay” but this time interval has not been clearly defined. Recent Findings: Data suggest that certain treatments such as earlier treatment with diuretics and vasodilators may improve patient symptom relief, morbidity, and mortality. Secondary analyses of clinical trials of novel treatments under development have not shown similar results. Summary: The data are equivocal regarding the impact of early treatment in AHF on in-hospital and long-term morbidity and mortality. Improved clinical trial designs will help answer when and if “early” treatment should begin and whether it impacts short- and long-term outcomes in AHF.",

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AU - Levy, Phillip D.

AU - Lindenfeld, Jo Ann

AU - Collins, Sean P.

PY - 2019/2/15

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AB - Purpose of Review: Acute heart failure accounts for over one million hospital discharges annually. Current guidelines suggest treatments for AHF should begin “without delay” but this time interval has not been clearly defined. Recent Findings: Data suggest that certain treatments such as earlier treatment with diuretics and vasodilators may improve patient symptom relief, morbidity, and mortality. Secondary analyses of clinical trials of novel treatments under development have not shown similar results. Summary: The data are equivocal regarding the impact of early treatment in AHF on in-hospital and long-term morbidity and mortality. Improved clinical trial designs will help answer when and if “early” treatment should begin and whether it impacts short- and long-term outcomes in AHF.

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Early Treatment in Emergency Department Patients with Acute Heart Failure: Does Time Matter?

Abstract

Keywords

ASJC Scopus subject areas

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