Early Treatment in Emergency Department Patients with Acute Heart Failure

Does Time Matter?

Anna Marie Chang, Peter S. Pang, Javed Butler, Alan B. Storrow, Phillip D. Levy, Jo Ann Lindenfeld, Sean P. Collins

Research output: Contribution to journalReview article

Abstract

Purpose of Review: Acute heart failure accounts for over one million hospital discharges annually. Current guidelines suggest treatments for AHF should begin “without delay” but this time interval has not been clearly defined. Recent Findings: Data suggest that certain treatments such as earlier treatment with diuretics and vasodilators may improve patient symptom relief, morbidity, and mortality. Secondary analyses of clinical trials of novel treatments under development have not shown similar results. Summary: The data are equivocal regarding the impact of early treatment in AHF on in-hospital and long-term morbidity and mortality. Improved clinical trial designs will help answer when and if “early” treatment should begin and whether it impacts short- and long-term outcomes in AHF.

Original languageEnglish (US)
Pages (from-to)12-20
Number of pages9
JournalCurrent Heart Failure Reports
Volume16
Issue number1
DOIs
StatePublished - Feb 15 2019
Externally publishedYes

Fingerprint

Hospital Emergency Service
Heart Failure
Therapeutics
Clinical Trials
Morbidity
Mortality
Vasodilator Agents
Diuretics
Guidelines

Keywords

  • Acute heart failure
  • Emergency medicine
  • Treatments for AHF

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Emergency Medicine

Cite this

Chang, A. M., Pang, P. S., Butler, J., Storrow, A. B., Levy, P. D., Lindenfeld, J. A., & Collins, S. P. (2019). Early Treatment in Emergency Department Patients with Acute Heart Failure: Does Time Matter? Current Heart Failure Reports, 16(1), 12-20. https://doi.org/10.1007/s11897-019-0419-y

Early Treatment in Emergency Department Patients with Acute Heart Failure : Does Time Matter? / Chang, Anna Marie; Pang, Peter S.; Butler, Javed; Storrow, Alan B.; Levy, Phillip D.; Lindenfeld, Jo Ann; Collins, Sean P.

In: Current Heart Failure Reports, Vol. 16, No. 1, 15.02.2019, p. 12-20.

Research output: Contribution to journalReview article

Chang, AM, Pang, PS, Butler, J, Storrow, AB, Levy, PD, Lindenfeld, JA & Collins, SP 2019, 'Early Treatment in Emergency Department Patients with Acute Heart Failure: Does Time Matter?', Current Heart Failure Reports, vol. 16, no. 1, pp. 12-20. https://doi.org/10.1007/s11897-019-0419-y
Chang, Anna Marie ; Pang, Peter S. ; Butler, Javed ; Storrow, Alan B. ; Levy, Phillip D. ; Lindenfeld, Jo Ann ; Collins, Sean P. / Early Treatment in Emergency Department Patients with Acute Heart Failure : Does Time Matter?. In: Current Heart Failure Reports. 2019 ; Vol. 16, No. 1. pp. 12-20.
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