Early renal allograft dysfunction: Report of a case with ultrastructural studies

Early renal allograft dysfunction is often associated with acute rejection (cellular or antibody mediated) or graft injury due to ischemia or surgical complications. Correlation of clinical, laboratory, and imaging studies are crucial in the assessment of patients with early graft dysfunction. Renal allograft biopsy is often necessary for diagnosis and to guide definitive therapy. We present a case of early graft dysfunction with an unusual clinical presentation and histologic picture. A high index of clinical suspicion along with electron microscopic studies led to the diagnosis.