Early Post-transplant Lymphoproliferative Disease in the Donor Ureter Without Systemic Involvement: A Case Report

W. M. Bennett, T. D. Batiuk, K. M. McEvoy, V. Douzdjian, J. Hyde, C. Shaut, G. M. Segal

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background Post-transplant lymphoproliferative disease is a serious complication of renal transplantation. Major risk factors include Epstein-Barr virus (EBV) seronegativity and induction immunosuppression with lymphocyte-depleting agents. Results We present a case of a 50-year year-old woman with very early onset PTLD confined to the donor ureter. Phenotypic studies on the tumor material reveal that the lymphoma was most likely of donor origin. A complete staging workup including the kidney allograft was negative for any other sites of involvement. Conclusions This case, which had a fatal outcome, emphasizes the risk of renal transplantation in BV-negative individuals when given induction with lymphocyte-depleting drugs.

Original languageEnglish (US)
Pages (from-to)2301-2303
Number of pages3
JournalTransplantation proceedings
Volume47
Issue number7
DOIs
StatePublished - Sep 1 2015

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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