Does the cerebellum play a role in podokinetic adaptation?

Gammon M. Earhart, William A. Fletcher, Fay Horak, Edward W. Block, Kimberly D. Weber, Oksana Suchowersky, Geoffrey Melvill Jones

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

After sustained stepping in-place on a rotating disc, healthy subjects will inadvertently turn in circles when asked to step in-place on a stationary surface with eyes closed. We asked whether the cerebellum is important for this adaptive phenomenon, called podokinetic after-rotation (PKAR). Subjects with cerebellar degeneration and age-matched control subjects performed 15 min of stepping in-place with eyes open on a rotating disc, then 30 min of attempting to step in-place with eyes closed on a stationary surface. Rotational velocity of PKAR was measured during this 30-min period. All control subjects demonstrated PKAR; average initial rotational velocity for control subjects was 16.4±3.5°/s. Five of the eight cerebellar subjects demonstrated impaired PK adaptation, defined as PKAR with an initial velocity more than two standard deviations below the control mean initial velocity. Average initial rotational velocity for cerebellar subjects was 7.8±0.2°/s. Impaired PK adaptation was not associated with impaired time constants of decay and was not correlated with variability of PKAR velocity. Our results suggest that the cerebellum is important for regulation of the amplitude of PK adaptation and that reduced PKAR amplitude is not likely the result of dyscoordination or variability of movement in the subjects tested.

Original languageEnglish (US)
Pages (from-to)538-542
Number of pages5
JournalExperimental Brain Research
Volume146
Issue number4
DOIs
StatePublished - 2002

Fingerprint

Cerebellum
Ataxia
Healthy Volunteers

Keywords

  • Cerebellum
  • Locomotion
  • Podokinetic
  • Sensorimotor adaptation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Earhart, G. M., Fletcher, W. A., Horak, F., Block, E. W., Weber, K. D., Suchowersky, O., & Jones, G. M. (2002). Does the cerebellum play a role in podokinetic adaptation? Experimental Brain Research, 146(4), 538-542. https://doi.org/10.1007/s00221-002-1238-y

Does the cerebellum play a role in podokinetic adaptation? / Earhart, Gammon M.; Fletcher, William A.; Horak, Fay; Block, Edward W.; Weber, Kimberly D.; Suchowersky, Oksana; Jones, Geoffrey Melvill.

In: Experimental Brain Research, Vol. 146, No. 4, 2002, p. 538-542.

Research output: Contribution to journalArticle

Earhart, GM, Fletcher, WA, Horak, F, Block, EW, Weber, KD, Suchowersky, O & Jones, GM 2002, 'Does the cerebellum play a role in podokinetic adaptation?', Experimental Brain Research, vol. 146, no. 4, pp. 538-542. https://doi.org/10.1007/s00221-002-1238-y
Earhart GM, Fletcher WA, Horak F, Block EW, Weber KD, Suchowersky O et al. Does the cerebellum play a role in podokinetic adaptation? Experimental Brain Research. 2002;146(4):538-542. https://doi.org/10.1007/s00221-002-1238-y
Earhart, Gammon M. ; Fletcher, William A. ; Horak, Fay ; Block, Edward W. ; Weber, Kimberly D. ; Suchowersky, Oksana ; Jones, Geoffrey Melvill. / Does the cerebellum play a role in podokinetic adaptation?. In: Experimental Brain Research. 2002 ; Vol. 146, No. 4. pp. 538-542.
@article{9393de3c5da0452d9e230f6ca7f0451c,
title = "Does the cerebellum play a role in podokinetic adaptation?",
abstract = "After sustained stepping in-place on a rotating disc, healthy subjects will inadvertently turn in circles when asked to step in-place on a stationary surface with eyes closed. We asked whether the cerebellum is important for this adaptive phenomenon, called podokinetic after-rotation (PKAR). Subjects with cerebellar degeneration and age-matched control subjects performed 15 min of stepping in-place with eyes open on a rotating disc, then 30 min of attempting to step in-place with eyes closed on a stationary surface. Rotational velocity of PKAR was measured during this 30-min period. All control subjects demonstrated PKAR; average initial rotational velocity for control subjects was 16.4±3.5°/s. Five of the eight cerebellar subjects demonstrated impaired PK adaptation, defined as PKAR with an initial velocity more than two standard deviations below the control mean initial velocity. Average initial rotational velocity for cerebellar subjects was 7.8±0.2°/s. Impaired PK adaptation was not associated with impaired time constants of decay and was not correlated with variability of PKAR velocity. Our results suggest that the cerebellum is important for regulation of the amplitude of PK adaptation and that reduced PKAR amplitude is not likely the result of dyscoordination or variability of movement in the subjects tested.",
keywords = "Cerebellum, Locomotion, Podokinetic, Sensorimotor adaptation",
author = "Earhart, {Gammon M.} and Fletcher, {William A.} and Fay Horak and Block, {Edward W.} and Weber, {Kimberly D.} and Oksana Suchowersky and Jones, {Geoffrey Melvill}",
year = "2002",
doi = "10.1007/s00221-002-1238-y",
language = "English (US)",
volume = "146",
pages = "538--542",
journal = "Experimental Brain Research",
issn = "0014-4819",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - Does the cerebellum play a role in podokinetic adaptation?

AU - Earhart, Gammon M.

AU - Fletcher, William A.

AU - Horak, Fay

AU - Block, Edward W.

AU - Weber, Kimberly D.

AU - Suchowersky, Oksana

AU - Jones, Geoffrey Melvill

PY - 2002

Y1 - 2002

N2 - After sustained stepping in-place on a rotating disc, healthy subjects will inadvertently turn in circles when asked to step in-place on a stationary surface with eyes closed. We asked whether the cerebellum is important for this adaptive phenomenon, called podokinetic after-rotation (PKAR). Subjects with cerebellar degeneration and age-matched control subjects performed 15 min of stepping in-place with eyes open on a rotating disc, then 30 min of attempting to step in-place with eyes closed on a stationary surface. Rotational velocity of PKAR was measured during this 30-min period. All control subjects demonstrated PKAR; average initial rotational velocity for control subjects was 16.4±3.5°/s. Five of the eight cerebellar subjects demonstrated impaired PK adaptation, defined as PKAR with an initial velocity more than two standard deviations below the control mean initial velocity. Average initial rotational velocity for cerebellar subjects was 7.8±0.2°/s. Impaired PK adaptation was not associated with impaired time constants of decay and was not correlated with variability of PKAR velocity. Our results suggest that the cerebellum is important for regulation of the amplitude of PK adaptation and that reduced PKAR amplitude is not likely the result of dyscoordination or variability of movement in the subjects tested.

AB - After sustained stepping in-place on a rotating disc, healthy subjects will inadvertently turn in circles when asked to step in-place on a stationary surface with eyes closed. We asked whether the cerebellum is important for this adaptive phenomenon, called podokinetic after-rotation (PKAR). Subjects with cerebellar degeneration and age-matched control subjects performed 15 min of stepping in-place with eyes open on a rotating disc, then 30 min of attempting to step in-place with eyes closed on a stationary surface. Rotational velocity of PKAR was measured during this 30-min period. All control subjects demonstrated PKAR; average initial rotational velocity for control subjects was 16.4±3.5°/s. Five of the eight cerebellar subjects demonstrated impaired PK adaptation, defined as PKAR with an initial velocity more than two standard deviations below the control mean initial velocity. Average initial rotational velocity for cerebellar subjects was 7.8±0.2°/s. Impaired PK adaptation was not associated with impaired time constants of decay and was not correlated with variability of PKAR velocity. Our results suggest that the cerebellum is important for regulation of the amplitude of PK adaptation and that reduced PKAR amplitude is not likely the result of dyscoordination or variability of movement in the subjects tested.

KW - Cerebellum

KW - Locomotion

KW - Podokinetic

KW - Sensorimotor adaptation

UR - http://www.scopus.com/inward/record.url?scp=0036387262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036387262&partnerID=8YFLogxK

U2 - 10.1007/s00221-002-1238-y

DO - 10.1007/s00221-002-1238-y

M3 - Article

VL - 146

SP - 538

EP - 542

JO - Experimental Brain Research

JF - Experimental Brain Research

SN - 0014-4819

IS - 4

ER -