@inproceedings{44247343f9234fa38b20e7890607e8f7,
title = "Discriminating the size and density of objects within tissue: Frequency-domain versus steady-state measurements",
abstract = " Steady-state (SS) optical measurements are simpler and less expensive than frequency-domain (FD) measurements. So why bother with FD? This paper illustrates the advantage obtained by FD vs. SS, using computer simulated experiments. A single shperical object is placed in the center of our model for the human prostate. The object is given a range of sized and values for its incremental absorption ((Delta) (mu) a ) above the background medium (bloodless prostate), with the condition that the optical volume (equals object volume X (Delta) (mu) a ) remains constant. Simulations of SS measurements and FD measurements using a 3 GHz modulation frequency were conducted and two measurements simulated: the frequency difference ((Delta) P equals phase with object-phase without object) and the relative amplitude (A/A 0 equals amplitude with object/amplitude without object). The results show that A/A 0 at SS and 3 GHz are very similar in their response to the object size, and the (Delta) P at 3 GHz offered important additional information.",
author = "Jacques, {Steven L.} and Hielscher, {Andreas H.}",
note = "Publisher Copyright: {\textcopyright} 2018 SPIE.; Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation ; Conference date: 01-02-1995 Through 28-02-1995",
year = "1995",
month = may,
day = "30",
doi = "10.1117/12.209971",
language = "English (US)",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
pages = "228--239",
editor = "Britton Chance and Alfano, {Robert R.}",
booktitle = "Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media",
}