Dietary Interventions and Multiple Sclerosis

Ghadah Altowaijri, Allison Fryman, Vijayshree Yadav

Research output: Contribution to journalReview article

15 Citations (Scopus)

Abstract

Multiple Sclerosis (MS) is a chronic, disabling neurologic disease that has its onset in young adulthood. While the knowledge about underlying pathogenesis of MS has improved significantly over the last few decades, the exact cause still eludes us. Despite the availability of several United States Food and Drug Administration-approved disease-modifying therapies (DMT) for MS in the last two decades, the disease remains disabling for many. DMT use is limited by its partial effectiveness, significant side effects in many cases, and high cost that leads people with MS (PwMS) to look for alternative management options. Dietary intervention as a possible mode to help MS seems very appealing to PwMS; however, scientific data supporting this notion remains sparse. New information on the role of various non-MS health factors, especially vascular disease risk factors such as hypertension, hyperlipidemia, salt intake, and obesity, that may play a role in MS pathogenesis appears very intriguing as it may partly explain the heterogeneity seen in MS activity and disability. This review will highlight the emerging information on various dietary approaches that may affect MS and their possible underlying mechanism.

Original languageEnglish (US)
Article number28
JournalCurrent Neurology and Neuroscience Reports
Volume17
Issue number3
DOIs
StatePublished - Mar 1 2017

Fingerprint

Multiple Sclerosis
Sclerosis
United States Food and Drug Administration
Hyperlipidemias
Nervous System Diseases
Vascular Diseases
Obesity
Salts
Hypertension
Costs and Cost Analysis
Health
Therapeutics

Keywords

  • Diet
  • MS pathogenesis
  • Multiple sclerosis
  • Nutrition
  • Obesity
  • Vascular disease risk factors

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Dietary Interventions and Multiple Sclerosis. / Altowaijri, Ghadah; Fryman, Allison; Yadav, Vijayshree.

In: Current Neurology and Neuroscience Reports, Vol. 17, No. 3, 28, 01.03.2017.

Research output: Contribution to journalReview article

@article{5f71dd76901140ac91494bf7aed899bb,
title = "Dietary Interventions and Multiple Sclerosis",
abstract = "Multiple Sclerosis (MS) is a chronic, disabling neurologic disease that has its onset in young adulthood. While the knowledge about underlying pathogenesis of MS has improved significantly over the last few decades, the exact cause still eludes us. Despite the availability of several United States Food and Drug Administration-approved disease-modifying therapies (DMT) for MS in the last two decades, the disease remains disabling for many. DMT use is limited by its partial effectiveness, significant side effects in many cases, and high cost that leads people with MS (PwMS) to look for alternative management options. Dietary intervention as a possible mode to help MS seems very appealing to PwMS; however, scientific data supporting this notion remains sparse. New information on the role of various non-MS health factors, especially vascular disease risk factors such as hypertension, hyperlipidemia, salt intake, and obesity, that may play a role in MS pathogenesis appears very intriguing as it may partly explain the heterogeneity seen in MS activity and disability. This review will highlight the emerging information on various dietary approaches that may affect MS and their possible underlying mechanism.",
keywords = "Diet, MS pathogenesis, Multiple sclerosis, Nutrition, Obesity, Vascular disease risk factors",
author = "Ghadah Altowaijri and Allison Fryman and Vijayshree Yadav",
year = "2017",
month = "3",
day = "1",
doi = "10.1007/s11910-017-0732-3",
language = "English (US)",
volume = "17",
journal = "Current Neurology and Neuroscience Reports",
issn = "1528-4042",
publisher = "Current Medicine Group",
number = "3",

}

TY - JOUR

T1 - Dietary Interventions and Multiple Sclerosis

AU - Altowaijri, Ghadah

AU - Fryman, Allison

AU - Yadav, Vijayshree

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Multiple Sclerosis (MS) is a chronic, disabling neurologic disease that has its onset in young adulthood. While the knowledge about underlying pathogenesis of MS has improved significantly over the last few decades, the exact cause still eludes us. Despite the availability of several United States Food and Drug Administration-approved disease-modifying therapies (DMT) for MS in the last two decades, the disease remains disabling for many. DMT use is limited by its partial effectiveness, significant side effects in many cases, and high cost that leads people with MS (PwMS) to look for alternative management options. Dietary intervention as a possible mode to help MS seems very appealing to PwMS; however, scientific data supporting this notion remains sparse. New information on the role of various non-MS health factors, especially vascular disease risk factors such as hypertension, hyperlipidemia, salt intake, and obesity, that may play a role in MS pathogenesis appears very intriguing as it may partly explain the heterogeneity seen in MS activity and disability. This review will highlight the emerging information on various dietary approaches that may affect MS and their possible underlying mechanism.

AB - Multiple Sclerosis (MS) is a chronic, disabling neurologic disease that has its onset in young adulthood. While the knowledge about underlying pathogenesis of MS has improved significantly over the last few decades, the exact cause still eludes us. Despite the availability of several United States Food and Drug Administration-approved disease-modifying therapies (DMT) for MS in the last two decades, the disease remains disabling for many. DMT use is limited by its partial effectiveness, significant side effects in many cases, and high cost that leads people with MS (PwMS) to look for alternative management options. Dietary intervention as a possible mode to help MS seems very appealing to PwMS; however, scientific data supporting this notion remains sparse. New information on the role of various non-MS health factors, especially vascular disease risk factors such as hypertension, hyperlipidemia, salt intake, and obesity, that may play a role in MS pathogenesis appears very intriguing as it may partly explain the heterogeneity seen in MS activity and disability. This review will highlight the emerging information on various dietary approaches that may affect MS and their possible underlying mechanism.

KW - Diet

KW - MS pathogenesis

KW - Multiple sclerosis

KW - Nutrition

KW - Obesity

KW - Vascular disease risk factors

UR - http://www.scopus.com/inward/record.url?scp=85015872286&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85015872286&partnerID=8YFLogxK

U2 - 10.1007/s11910-017-0732-3

DO - 10.1007/s11910-017-0732-3

M3 - Review article

C2 - 28317084

AN - SCOPUS:85015872286

VL - 17

JO - Current Neurology and Neuroscience Reports

JF - Current Neurology and Neuroscience Reports

SN - 1528-4042

IS - 3

M1 - 28

ER -