Diagnostic imaging of malignant melanoma with radiolabeled antitumor antibodies

S. M. Larson; J. A. Carrasquillo; K. A. Krohn; R. W. McGuffin; D. L. Williams; I. Hellström; D. Lyster

doi:10.1001/jama.249.6.811

Diagnostic imaging of malignant melanoma with radiolabeled antitumor antibodies

S. M. Larson, J. A. Carrasquillo, K. A. Krohn, R. W. McGuffin, D. L. Williams, I. Hellström, D. Lyster

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Tumor-specific monoclonal antibodies offer the potential for improved diagnosis of and therapy for malignant neoplasms. We have used iodine 131- and iodine 123-radiolabeled murine monoclonal immunoglobulin and Fab fragments against p97, a 97,000 molecular weight, melanoma-associated antigen on the cell surface, to image metastatic tumor deposits in patients with malignant melanoma.

Original language	English (US)
Pages (from-to)	811-812
Number of pages	2
Journal	Journal of the American Medical Association
Volume	249
Issue number	6
DOIs	https://doi.org/10.1001/jama.249.6.811
State	Published - 1983
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1001/jama.249.6.811

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title = "Diagnostic imaging of malignant melanoma with radiolabeled antitumor antibodies",

abstract = "Tumor-specific monoclonal antibodies offer the potential for improved diagnosis of and therapy for malignant neoplasms. We have used iodine 131- and iodine 123-radiolabeled murine monoclonal immunoglobulin and Fab fragments against p97, a 97,000 molecular weight, melanoma-associated antigen on the cell surface, to image metastatic tumor deposits in patients with malignant melanoma.",

author = "Larson, {S. M.} and Carrasquillo, {J. A.} and Krohn, {K. A.} and McGuffin, {R. W.} and Williams, {D. L.} and I. Hellstr{\"o}m and D. Lyster",

year = "1983",

doi = "10.1001/jama.249.6.811",

language = "English (US)",

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T1 - Diagnostic imaging of malignant melanoma with radiolabeled antitumor antibodies

AU - Larson, S. M.

AU - Carrasquillo, J. A.

AU - Krohn, K. A.

AU - McGuffin, R. W.

AU - Williams, D. L.

AU - Hellström, I.

AU - Lyster, D.

PY - 1983

Y1 - 1983

N2 - Tumor-specific monoclonal antibodies offer the potential for improved diagnosis of and therapy for malignant neoplasms. We have used iodine 131- and iodine 123-radiolabeled murine monoclonal immunoglobulin and Fab fragments against p97, a 97,000 molecular weight, melanoma-associated antigen on the cell surface, to image metastatic tumor deposits in patients with malignant melanoma.

AB - Tumor-specific monoclonal antibodies offer the potential for improved diagnosis of and therapy for malignant neoplasms. We have used iodine 131- and iodine 123-radiolabeled murine monoclonal immunoglobulin and Fab fragments against p97, a 97,000 molecular weight, melanoma-associated antigen on the cell surface, to image metastatic tumor deposits in patients with malignant melanoma.

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JF - Journal of the American Medical Association

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Diagnostic imaging of malignant melanoma with radiolabeled antitumor antibodies

Abstract

ASJC Scopus subject areas

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