Diabetic nephropathy and proximal tubule ROS: Challenging our glomerulocentricity

S. P. Bagby

doi:10.1038/sj.ki.5002286

Diabetic nephropathy and proximal tubule ROS: Challenging our glomerulocentricity

S. P. Bagby

Nephrology and Hypertension

Research output: Contribution to journal › Comment/debate › peer-review

41 Scopus citations

Abstract

Diabetic nephropathy is currently viewed as a predominantly glomerular process with glomerular injury driving secondary tubular loss. Brezniceanu and colleagues apply transgenic methods to support a prominent role for reactive oxygen species as mediators and for the proximal tubule as a major site of early disease activity in diabetes. Results support evidence for early tubular apoptosis and atrophy in human diabetic nephropathy.

Original language	English (US)
Pages (from-to)	1199-1202
Number of pages	4
Journal	Kidney International
Volume	71
Issue number	12
DOIs	https://doi.org/10.1038/sj.ki.5002286
State	Published - Jun 2007

ASJC Scopus subject areas

Nephrology

Access to Document

10.1038/sj.ki.5002286

Cite this

@article{0568330769b843f697fbd087e0aebc84,

title = "Diabetic nephropathy and proximal tubule ROS: Challenging our glomerulocentricity",

abstract = "Diabetic nephropathy is currently viewed as a predominantly glomerular process with glomerular injury driving secondary tubular loss. Brezniceanu and colleagues apply transgenic methods to support a prominent role for reactive oxygen species as mediators and for the proximal tubule as a major site of early disease activity in diabetes. Results support evidence for early tubular apoptosis and atrophy in human diabetic nephropathy.",

author = "Bagby, {S. P.}",

year = "2007",

month = jun,

doi = "10.1038/sj.ki.5002286",

language = "English (US)",

volume = "71",

pages = "1199--1202",

journal = "Kidney International",

issn = "0085-2538",

publisher = "Nature Publishing Group",

number = "12",

}

TY - JOUR

T1 - Diabetic nephropathy and proximal tubule ROS

T2 - Challenging our glomerulocentricity

AU - Bagby, S. P.

PY - 2007/6

Y1 - 2007/6

N2 - Diabetic nephropathy is currently viewed as a predominantly glomerular process with glomerular injury driving secondary tubular loss. Brezniceanu and colleagues apply transgenic methods to support a prominent role for reactive oxygen species as mediators and for the proximal tubule as a major site of early disease activity in diabetes. Results support evidence for early tubular apoptosis and atrophy in human diabetic nephropathy.

AB - Diabetic nephropathy is currently viewed as a predominantly glomerular process with glomerular injury driving secondary tubular loss. Brezniceanu and colleagues apply transgenic methods to support a prominent role for reactive oxygen species as mediators and for the proximal tubule as a major site of early disease activity in diabetes. Results support evidence for early tubular apoptosis and atrophy in human diabetic nephropathy.

UR - http://www.scopus.com/inward/record.url?scp=34250026180&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34250026180&partnerID=8YFLogxK

U2 - 10.1038/sj.ki.5002286

DO - 10.1038/sj.ki.5002286

M3 - Comment/debate

C2 - 17554351

AN - SCOPUS:34250026180

SN - 0085-2538

VL - 71

SP - 1199

EP - 1202

JO - Kidney International

JF - Kidney International

IS - 12

ER -

Diabetic nephropathy and proximal tubule ROS: Challenging our glomerulocentricity

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this