TY - JOUR
T1 - Diabetes-related changes in hearing
AU - Austin, Donald F.
AU - Konrad-Martin, Dawn
AU - Griest, Susan
AU - McMillan, Garnett P.
AU - McDermott, Daniel
AU - Fausti, Stephen
PY - 2009/9
Y1 - 2009/9
N2 - Objectives/Hypothesis: Determine the effects on hearing of diabetes mellitus (DM) severity.Study Design: We conducted a cross-sectional study among Veterans to investigate the relationship of diabetes severity and hearing in randomly selected subjects with (165) and without (137) DM and who had no more than a moderate hearing loss.Methods: Subjects were classified by three age tertiles (<50, 50-56, and 57p years). Diabetes severity was classified as insulin-dependent (IDDM), noninsulin-dependent (NIDDM), or no DM. Other DM measures included concurrent serum glucose, serum HbA1c, duration of disease, and several measures of DM-related complications. Pure-tone thresholds were measured in both ears of each subject at frequencies from 250 Hz through 14, 000 Hz. Outcome measures were adjusted for age and frequency and analyzed for differences between subject groups using analysis of variance. Contrasts of the mean NIDDM and IDDM thresholds at each frequency to the DM group, and controlled for the effects of frequency, age, and interactions were modeled.Results: There was greater hearing loss in younger tertile DM subjects compared to those without DM. Significant hearing differences were at all frequencies for NIDDM subjects, but for IDDM subjects, differences were at 1, 000 Hz and below, and 10, 000 Hz and above. Over age 50 years, there were significant associations between hearing at low frequencies and IDDM only. Self-report of prior noise exposure did not explain observed differences.Conclusions: Diabetes is associated with an increased risk of hearing loss, and this difference is manifest particularly in adults <50 years old.
AB - Objectives/Hypothesis: Determine the effects on hearing of diabetes mellitus (DM) severity.Study Design: We conducted a cross-sectional study among Veterans to investigate the relationship of diabetes severity and hearing in randomly selected subjects with (165) and without (137) DM and who had no more than a moderate hearing loss.Methods: Subjects were classified by three age tertiles (<50, 50-56, and 57p years). Diabetes severity was classified as insulin-dependent (IDDM), noninsulin-dependent (NIDDM), or no DM. Other DM measures included concurrent serum glucose, serum HbA1c, duration of disease, and several measures of DM-related complications. Pure-tone thresholds were measured in both ears of each subject at frequencies from 250 Hz through 14, 000 Hz. Outcome measures were adjusted for age and frequency and analyzed for differences between subject groups using analysis of variance. Contrasts of the mean NIDDM and IDDM thresholds at each frequency to the DM group, and controlled for the effects of frequency, age, and interactions were modeled.Results: There was greater hearing loss in younger tertile DM subjects compared to those without DM. Significant hearing differences were at all frequencies for NIDDM subjects, but for IDDM subjects, differences were at 1, 000 Hz and below, and 10, 000 Hz and above. Over age 50 years, there were significant associations between hearing at low frequencies and IDDM only. Self-report of prior noise exposure did not explain observed differences.Conclusions: Diabetes is associated with an increased risk of hearing loss, and this difference is manifest particularly in adults <50 years old.
KW - Audiologic monitoring
KW - Hearing loss
KW - Veterans
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U2 - 10.1002/lary.20570
DO - 10.1002/lary.20570
M3 - Article
C2 - 19593813
AN - SCOPUS:70349595246
SN - 0023-852X
VL - 119
SP - 1788
EP - 1796
JO - Laryngoscope
JF - Laryngoscope
IS - 9
ER -