Development of a symptomatic intracranial meningioma in a male-to-female transsexual after initiation of hormone therapy

Amy R. Deipolyi, Seunggu (Jude) Han, Andrew T. Parsa

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Transsexual patients are routinely treated with sex hormone therapy, which may be a risk factor for meningiomas, although the data are largely inconclusive. Here we describe a male-to-female transsexual patient treated with estradiol patches, who developed an occipital meningioma causing generalized seizures. This is the second report of a male-to-female transsexual patient who developed a symptomatic meningioma after sex hormone treatment, adding to the growing evidence that sex hormones contribute to the pathogenesis of meningiomas. Meningiomas may therefore complicate hormone therapy and sex hormones may be contraindicated in transsexual candidates with meningiomas identified upon screening.

Original languageEnglish (US)
Pages (from-to)1324-1326
Number of pages3
JournalJournal of Clinical Neuroscience
Volume17
Issue number10
DOIs
StatePublished - Oct 1 2010
Externally publishedYes

Fingerprint

Meningioma
Gonadal Steroid Hormones
Hormones
Therapeutics
Estradiol
Seizures

Keywords

  • Meningioma
  • Sex hormone
  • Transsexual

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

Cite this

Development of a symptomatic intracranial meningioma in a male-to-female transsexual after initiation of hormone therapy. / Deipolyi, Amy R.; Han, Seunggu (Jude); Parsa, Andrew T.

In: Journal of Clinical Neuroscience, Vol. 17, No. 10, 01.10.2010, p. 1324-1326.

Research output: Contribution to journalArticle

@article{3efc9cec11814411863a9ddc65050113,
title = "Development of a symptomatic intracranial meningioma in a male-to-female transsexual after initiation of hormone therapy",
abstract = "Transsexual patients are routinely treated with sex hormone therapy, which may be a risk factor for meningiomas, although the data are largely inconclusive. Here we describe a male-to-female transsexual patient treated with estradiol patches, who developed an occipital meningioma causing generalized seizures. This is the second report of a male-to-female transsexual patient who developed a symptomatic meningioma after sex hormone treatment, adding to the growing evidence that sex hormones contribute to the pathogenesis of meningiomas. Meningiomas may therefore complicate hormone therapy and sex hormones may be contraindicated in transsexual candidates with meningiomas identified upon screening.",
keywords = "Meningioma, Sex hormone, Transsexual",
author = "Deipolyi, {Amy R.} and Han, {Seunggu (Jude)} and Parsa, {Andrew T.}",
year = "2010",
month = "10",
day = "1",
doi = "10.1016/j.jocn.2010.01.036",
language = "English (US)",
volume = "17",
pages = "1324--1326",
journal = "Journal of Clinical Neuroscience",
issn = "0967-5868",
publisher = "Churchill Livingstone",
number = "10",

}

TY - JOUR

T1 - Development of a symptomatic intracranial meningioma in a male-to-female transsexual after initiation of hormone therapy

AU - Deipolyi, Amy R.

AU - Han, Seunggu (Jude)

AU - Parsa, Andrew T.

PY - 2010/10/1

Y1 - 2010/10/1

N2 - Transsexual patients are routinely treated with sex hormone therapy, which may be a risk factor for meningiomas, although the data are largely inconclusive. Here we describe a male-to-female transsexual patient treated with estradiol patches, who developed an occipital meningioma causing generalized seizures. This is the second report of a male-to-female transsexual patient who developed a symptomatic meningioma after sex hormone treatment, adding to the growing evidence that sex hormones contribute to the pathogenesis of meningiomas. Meningiomas may therefore complicate hormone therapy and sex hormones may be contraindicated in transsexual candidates with meningiomas identified upon screening.

AB - Transsexual patients are routinely treated with sex hormone therapy, which may be a risk factor for meningiomas, although the data are largely inconclusive. Here we describe a male-to-female transsexual patient treated with estradiol patches, who developed an occipital meningioma causing generalized seizures. This is the second report of a male-to-female transsexual patient who developed a symptomatic meningioma after sex hormone treatment, adding to the growing evidence that sex hormones contribute to the pathogenesis of meningiomas. Meningiomas may therefore complicate hormone therapy and sex hormones may be contraindicated in transsexual candidates with meningiomas identified upon screening.

KW - Meningioma

KW - Sex hormone

KW - Transsexual

UR - http://www.scopus.com/inward/record.url?scp=77955660312&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955660312&partnerID=8YFLogxK

U2 - 10.1016/j.jocn.2010.01.036

DO - 10.1016/j.jocn.2010.01.036

M3 - Article

VL - 17

SP - 1324

EP - 1326

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

SN - 0967-5868

IS - 10

ER -